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Systemic inflammatory Th1 cytokines during Trypanosoma cruzi infection disrupt the typical anatomical cell distribution and phenotypic/functional characteristics of various cell subsets within the thymus.
Microbes Infect. 2024 Apr 13:105337. doi: 10.1016/j.micinf.2024.105337. Online ahead of print.
Microbes Infect. 2024.
PMID: 38615883
The high identity of the Trypanosoma cruzi Group-I of trans-sialidases points them as promising vaccine immunogens.
Pacini MF, Perdomini A, Bulfoni Balbi C, Dinatale B, Herrera FE, Perez AR, Marcipar I.
Pacini MF, et al. Among authors: bulfoni balbi c.
Proteins. 2023 Oct;91(10):1444-1460. doi: 10.1002/prot.26537. Epub 2023 Jun 16.
Proteins. 2023.
PMID: 37323089
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Nasal immunization with a L. lactis-derived trans-sialidase antigen plus c-di-AMP protects against acute oral T. cruzi infection.
Pacini MF, González FB, Dinatale B, Bulfoni Balbi C, Villar SR, Farré C, Lupi G, Espariz M, Blancato VS, Magni C, Marcipar I, Pérez AR.
Pacini MF, et al. Among authors: bulfoni balbi c.
Vaccine. 2022 Apr 1;40(15):2311-2323. doi: 10.1016/j.vaccine.2022.02.071. Epub 2022 Mar 9.
Vaccine. 2022.
PMID: 35279330
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