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Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo.
Nucleic Acids Res. 2024 May 22;52(9):4799-4817. doi: 10.1093/nar/gkae260.
Nucleic Acids Res. 2024.
PMID: 38613388
Free PMC article.
G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects.
Wang F, Calvo-Roitberg E, Rembetsy-Brown JM, Fang M, Sousa J, Kartje ZJ, Krishnamurthy PM, Lee J, Green MR, Pai AA, Watts JK.
Wang F, et al. Among authors: rembetsy brown jm.
Nucleic Acids Res. 2022 Dec 9;50(22):12657-12673. doi: 10.1093/nar/gkac1108.
Nucleic Acids Res. 2022.
PMID: 36511872
Free PMC article.
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Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts.
Shin M, Chan IL, Cao Y, Gruntman AM, Lee J, Sousa J, Rodríguez TC, Echeverria D, Devi G, Debacker AJ, Moazami MP, Krishnamurthy PM, Rembetsy-Brown JM, Kelly K, Yukselen O, Donnard E, Parsons TJ, Khvorova A, Sontheimer EJ, Maehr R, Garber M, Watts JK.
Shin M, et al. Among authors: rembetsy brown jm.
Nucleic Acids Res. 2022 Aug 26;50(15):8418-8430. doi: 10.1093/nar/gkac630.
Nucleic Acids Res. 2022.
PMID: 35920332
Free PMC article.
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