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Crystal structure of nucleotide-free dynamin.
Faelber K, Posor Y, Gao S, Held M, Roske Y, Schulze D, Haucke V, Noé F, Daumke O. Faelber K, et al. Among authors: roske y. Nature. 2011 Sep 18;477(7366):556-60. doi: 10.1038/nature10369. Nature. 2011. PMID: 21927000
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan A, Roske Y, Barth C, Forero LL, Bravo-Rodriguez K, Redel A, Kostova S, McShane E, Opitz R, Faelber K, Rau K, Mielke T, Daumke O, Selbach M, Sanchez-Garcia E, Rocks O, Panáková D, Heinemann U, Wanker EE. Arumughan A, et al. Among authors: roske y. Nat Commun. 2016 Oct 20;7:13047. doi: 10.1038/ncomms13047. Nat Commun. 2016. PMID: 27762274 Free PMC article.
Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo WT, Zhang Y, Vadas O, Roske Y, Gulluni F, De Santis MC, Zagar AV, Stephanowitz H, Hirsch E, Liu F, Daumke O, Kudryashev M, Haucke V. Lo WT, et al. Among authors: roske y. Nat Struct Mol Biol. 2022 Mar;29(3):218-228. doi: 10.1038/s41594-022-00730-w. Epub 2022 Mar 7. Nat Struct Mol Biol. 2022. PMID: 35256802 Free PMC article.
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo WT, Belabed H, Kücükdisli M, Metag J, Roske Y, Prokofeva P, Ohashi Y, Horatscheck A, Cirillo D, Krauss M, Schmied C, Neuenschwander M, von Kries JP, Médard G, Kuster B, Perisic O, Williams RL, Daumke O, Payrastre B, Severin S, Nazaré M, Haucke V. Lo WT, et al. Among authors: roske y. Nat Chem Biol. 2023 Jan;19(1):18-27. doi: 10.1038/s41589-022-01118-z. Epub 2022 Sep 15. Nat Chem Biol. 2023. PMID: 36109648 Free PMC article.
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous ET, Stolzenberg S, Sticht J, Wieczorek M, Roske Y, Günther M, Dähn S, Boesen BB, Calvo MM, Biese C, Kuppler F, Medina-García Á, Álvaro-Benito M, Höfer T, Noé F, Freund C. Abualrous ET, et al. Among authors: roske y. Nat Chem Biol. 2023 Oct;19(10):1196-1204. doi: 10.1038/s41589-023-01316-3. Epub 2023 May 4. Nat Chem Biol. 2023. PMID: 37142807 Free PMC article.
44 results