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Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro.
Selvarajan I, Kiema M, Huang RT, Li J, Zhu J, Pölönen P, Örd T, Õunap K, Godiwala M, Golebiewski AK, Ravindran A, Mäklin K, Toropainen A, Stolze LK, Arce M, Magnusson PU, White S, Romanoski CE, Heinäniemi M, Laakkonen JP, Fang Y, Kaikkonen MU. Selvarajan I, et al. Among authors: laakkonen jp. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1330-1345. doi: 10.1161/ATVBAHA.123.318964. Epub 2024 Apr 11. Arterioscler Thromb Vasc Biol. 2024. PMID: 38602103 Free article.
Profiling of Primary and Mature miRNA Expression in Atherosclerosis-Associated Cell Types.
Moreau PR, Tomas Bosch V, Bouvy-Liivrand M, Õunap K, Örd T, Pulkkinen HH, Pölönen P, Heinäniemi M, Ylä-Herttuala S, Laakkonen JP, Linna-Kuosmanen S, Kaikkonen MU. Moreau PR, et al. Among authors: laakkonen jp. Arterioscler Thromb Vasc Biol. 2021 Jul;41(7):2149-2167. doi: 10.1161/ATVBAHA.121.315579. Epub 2021 May 13. Arterioscler Thromb Vasc Biol. 2021. PMID: 33980036 Free PMC article.
Large Vessel Cell Heterogeneity and Plasticity: Focus in Aortic Aneurysms.
Jauhiainen S, Kiema M, Hedman M, Laakkonen JP. Jauhiainen S, et al. Among authors: laakkonen jp. Arterioscler Thromb Vasc Biol. 2022 Jul;42(7):811-818. doi: 10.1161/ATVBAHA.121.316237. Epub 2022 May 19. Arterioscler Thromb Vasc Biol. 2022. PMID: 35587695 Free article. Review.
Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures.
Örd T, Lönnberg T, Nurminen V, Ravindran A, Niskanen H, Kiema M, Õunap K, Maria M, Moreau PR, Mishra PP, Palani S, Virta J, Liljenbäck H, Aavik E, Roivainen A, Ylä-Herttuala S, Laakkonen JP, Lehtimäki T, Kaikkonen MU. Örd T, et al. Among authors: laakkonen jp. Am J Hum Genet. 2023 May 4;110(5):722-740. doi: 10.1016/j.ajhg.2023.03.013. Epub 2023 Apr 14. Am J Hum Genet. 2023. PMID: 37060905 Free PMC article.
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis.
Ravindran A, Holappa L, Niskanen H, Skovorodkin I, Kaisto S, Beter M, Kiema M, Selvarajan I, Nurminen V, Aavik E, Aherrahrou R, Pasonen-Seppänen S, Fortino V, Laakkonen JP, Ylä-Herttuala S, Vainio S, Örd T, Kaikkonen MU. Ravindran A, et al. Among authors: laakkonen jp. Cardiovasc Res. 2024 Jan 30:cvae028. doi: 10.1093/cvr/cvae028. Online ahead of print. Cardiovasc Res. 2024. PMID: 38289873
BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF.
Pulkkinen HH, Kiema M, Lappalainen JP, Toropainen A, Beter M, Tirronen A, Holappa L, Niskanen H, Kaikkonen MU, Ylä-Herttuala S, Laakkonen JP. Pulkkinen HH, et al. Among authors: laakkonen jp. Angiogenesis. 2021 Feb;24(1):129-144. doi: 10.1007/s10456-020-09748-4. Epub 2020 Oct 6. Angiogenesis. 2021. PMID: 33021694 Free PMC article.
Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology.
Jauhiainen S, Onyeogaziri FC, Lazzaroni F, Conze LL, Laakkonen JP, Laham-Karam N, Laakso A, Niemelä M, Rezai Jahromi B, Magnusson PU. Jauhiainen S, et al. Among authors: laakkonen jp. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167139. doi: 10.1016/j.bbadis.2024.167139. Epub 2024 Mar 26. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38537685
Wall Shear Stress Predicts Media Degeneration and Biomechanical Changes in Thoracic Aorta.
Kiema M, Sarin JK, Kauhanen SP, Torniainen J, Matikka H, Luoto ES, Jaakkola P, Saari P, Liimatainen T, Vanninen R, Ylä-Herttuala S, Hedman M, Laakkonen JP. Kiema M, et al. Among authors: laakkonen jp. Front Physiol. 2022 Jul 7;13:934941. doi: 10.3389/fphys.2022.934941. eCollection 2022. Front Physiol. 2022. PMID: 35874533 Free PMC article.
42 results