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Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation.
Hiyoshi H, Sakuma K, Asano S, Napier SC, Konagaya S, Mochida T, Ueno H, Watanabe T, Kassai Y, Matsumoto H, Ito R, Toyoda T. Hiyoshi H, et al. Among authors: toyoda t. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2320883121. doi: 10.1073/pnas.2320883121. Epub 2024 Apr 10. Proc Natl Acad Sci U S A. 2024. PMID: 38598342 Free PMC article.
Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting.
Tsujisaka Y, Hatani T, Okubo C, Ito R, Kimura A, Narita M, Chonabayashi K, Funakoshi S, Lucena-Cacace A, Toyoda T, Osafune K, Kimura T, Saito H, Yoshida Y. Tsujisaka Y, et al. Among authors: toyoda t. Stem Cell Reports. 2022 Jul 12;17(7):1772-1785. doi: 10.1016/j.stemcr.2022.05.003. Epub 2022 Jun 9. Stem Cell Reports. 2022. PMID: 35688152 Free PMC article.
Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells.
Kondo Y, Toyoda T, Ito R, Funato M, Hosokawa Y, Matsui S, Sudo T, Nakamura M, Okada C, Zhuang X, Watanabe A, Ohta A, Inagaki N, Osafune K. Kondo Y, et al. Among authors: toyoda t. Diabetologia. 2017 Aug;60(8):1454-1466. doi: 10.1007/s00125-017-4302-7. Epub 2017 May 22. Diabetologia. 2017. PMID: 28534195
iPSC technology-based regenerative therapy for diabetes.
Kondo Y, Toyoda T, Inagaki N, Osafune K. Kondo Y, et al. Among authors: toyoda t. J Diabetes Investig. 2018 Mar;9(2):234-243. doi: 10.1111/jdi.12702. Epub 2017 Jul 29. J Diabetes Investig. 2018. PMID: 28609558 Free PMC article. Review.
758 results