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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection.
Cooper L, Xu H, Polmear J, Kealy L, Szeto C, Pang ES, Gupta M, Kirn A, Taylor JJ, Jackson KJL, Broomfield BJ, Nguyen A, Gago da Graça C, La Gruta N, Utzschneider DT, Groom JR, Martelotto L, Parish IA, O'Keeffe M, Scharer CD, Gras S, Good-Jacobson KL. Cooper L, et al. Among authors: scharer cd. Immunity. 2024 May 14;57(5):1037-1055.e6. doi: 10.1016/j.immuni.2024.03.016. Epub 2024 Apr 8. Immunity. 2024. PMID: 38593796
Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection.
Di Pietro A, Polmear J, Cooper L, Damelang T, Hussain T, Hailes L, O'Donnell K, Udupa V, Mi T, Preston S, Shtewe A, Hershberg U, Turner SJ, La Gruta NL, Chung AW, Tarlinton DM, Scharer CD, Good-Jacobson KL. Di Pietro A, et al. Among authors: scharer cd. Nat Immunol. 2022 Jan;23(1):86-98. doi: 10.1038/s41590-021-01077-y. Epub 2021 Nov 29. Nat Immunol. 2022. PMID: 34845392
A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans.
Nellore A, Zumaquero E, Scharer CD, Fucile CF, Tipton CM, King RG, Mi T, Mousseau B, Bradley JE, Zhou F, Mutneja S, Goepfert PA, Boss JM, Randall TD, Sanz I, Rosenberg AF, Lund FE. Nellore A, et al. Among authors: scharer cd. Immunity. 2023 Apr 11;56(4):847-863.e8. doi: 10.1016/j.immuni.2023.03.001. Epub 2023 Mar 22. Immunity. 2023. PMID: 36958335 Free PMC article.
T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells.
Stone SL, Peel JN, Scharer CD, Risley CA, Chisolm DA, Schultz MD, Yu B, Ballesteros-Tato A, Wojciechowski W, Mousseau B, Misra RS, Hanidu A, Jiang H, Qi Z, Boss JM, Randall TD, Brodeur SR, Goldrath AW, Weinmann AS, Rosenberg AF, Lund FE. Stone SL, et al. Among authors: scharer cd. Immunity. 2019 May 21;50(5):1172-1187.e7. doi: 10.1016/j.immuni.2019.04.004. Epub 2019 May 7. Immunity. 2019. PMID: 31076359 Free PMC article.
80 results