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Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models.
Li F, Bondra KM, Ghilu S, Studebaker A, Liu Q, Michalek JE, Kogiso M, Li XN, Kalapurakal JA, James CD, Burma S, Kurmasheva RT, Houghton PJ. Li F, et al. Among authors: houghton pj. Clin Cancer Res. 2022 Sep 1;28(17):3836-3849. doi: 10.1158/1078-0432.CCR-22-1052. Clin Cancer Res. 2022. PMID: 35797217 Free PMC article.
Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant Rhabdomyosarcoma.
Garcia N, Del Pozo V, Yohe ME, Goodwin CM, Shackleford TJ, Wang L, Baxi K, Chen Y, Rogojina AT, Zimmerman SM, Peer CJ, Figg WD, Ignatius MS, Wood KC, Houghton PJ, Vaseva AV. Garcia N, et al. Among authors: houghton pj. Mol Cancer Ther. 2022 Jan;21(1):170-183. doi: 10.1158/1535-7163.MCT-21-0194. Epub 2021 Nov 4. Mol Cancer Ther. 2022. PMID: 34737198 Free PMC article.
Extrarenal Anaplastic Wilms Tumor: A Case Report With Genomic Analysis and Tumor Models.
Willis KR, Sathe AA, Xing C, Koduru P, Artunduaga M, Butler EB, Park JY, Kurmasheva RT, Houghton PJ, Chen KS, Rakheja D. Willis KR, et al. Among authors: houghton pj. J Pediatr Hematol Oncol. 2022 May 1;44(4):147-154. doi: 10.1097/MPH.0000000000002413. Epub 2022 Feb 4. J Pediatr Hematol Oncol. 2022. PMID: 35129140 Free PMC article.
589 results