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Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance.
Bozadjieva-Kramer N, Shin JH, Li Z, Rupp AC, Miller N, Kernodle S, Lanthier N, Henry P, Seshadri N, Myronovych A, MacDougald OA, O'Rourke RW, Kohli R, Burant CF, Rothberg AE, Seeley RJ. Bozadjieva-Kramer N, et al. Among authors: macdougald oa. JCI Insight. 2024 Apr 8;9(7):e174164. doi: 10.1172/jci.insight.174164. JCI Insight. 2024. PMID: 38587078 Free PMC article.
Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon RC, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung JN, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mori H, et al. Among authors: macdougald oa. Mol Metab. 2024 May;83:101916. doi: 10.1016/j.molmet.2024.101916. Epub 2024 Mar 14. Mol Metab. 2024. PMID: 38492843 Free PMC article.
Wnt signaling preserves progenitor cell multipotency during adipose tissue development.
Yang Loureiro Z, Joyce S, DeSouza T, Solivan-Rivera J, Desai A, Skritakis P, Yang Q, Ziegler R, Zhong D, Nguyen TT, MacDougald OA, Corvera S. Yang Loureiro Z, et al. Among authors: macdougald oa. Nat Metab. 2023 Jun;5(6):1014-1028. doi: 10.1038/s42255-023-00813-y. Epub 2023 Jun 19. Nat Metab. 2023. PMID: 37337125 Free PMC article.
Dietary lipid is largely deposited in skin and rapidly affects insulating properties.
Riley N, Kasza I, Barrett-Wilt G, Michaud J, Jain R, Trautman ME, Simcox JA, Yen CE, MacDougald OA, Lamming DW, Alexander CM. Riley N, et al. Among authors: macdougald oa. Res Sq [Preprint]. 2024 Feb 22:rs.3.rs-3957002. doi: 10.21203/rs.3.rs-3957002/v1. Res Sq. 2024. PMID: 38464106 Free PMC article. Preprint.
SCD1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon R, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung J, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mori H, et al. Among authors: macdougald oa. bioRxiv [Preprint]. 2023 Oct 27:2023.10.27.564376. doi: 10.1101/2023.10.27.564376. bioRxiv. 2023. PMID: 37961537 Free PMC article. Updated. Preprint.
173 results