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Lobelane decreases methamphetamine self-administration in rats.
Neugebauer NM, Harrod SB, Stairs DJ, Crooks PA, Dwoskin LP, Bardo MT. Neugebauer NM, et al. Among authors: bardo mt. Eur J Pharmacol. 2007 Sep 24;571(1):33-8. doi: 10.1016/j.ejphar.2007.06.003. Epub 2007 Jun 13. Eur J Pharmacol. 2007. PMID: 17612524 Free PMC article.
Nicotinic receptor-based therapeutics and candidates for smoking cessation.
Dwoskin LP, Smith AM, Wooters TE, Zhang Z, Crooks PA, Bardo MT. Dwoskin LP, et al. Among authors: bardo mt. Biochem Pharmacol. 2009 Oct 1;78(7):732-43. doi: 10.1016/j.bcp.2009.06.002. Epub 2009 Jun 10. Biochem Pharmacol. 2009. PMID: 19523455 Free PMC article. Review.
Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release.
Smith AM, Pivavarchyk M, Wooters TE, Zhang Z, Zheng G, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP. Smith AM, et al. Among authors: bardo mt. Biochem Pharmacol. 2010 Aug 1;80(3):402-9. doi: 10.1016/j.bcp.2010.03.018. Epub 2010 Mar 25. Biochem Pharmacol. 2010. PMID: 20346923 Free PMC article.
The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.
Beckmann JS, Siripurapu KB, Nickell JR, Horton DB, Denehy ED, Vartak A, Crooks PA, Dwoskin LP, Bardo MT. Beckmann JS, et al. Among authors: bardo mt. J Pharmacol Exp Ther. 2010 Dec;335(3):841-51. doi: 10.1124/jpet.110.172742. Epub 2010 Aug 30. J Pharmacol Exp Ther. 2010. PMID: 20805303 Free PMC article.
246 results