Moore DJ - Search Results

1

Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials initiative.

Wyse RK, Isaacs T, Barker RA, Cookson MR, Dawson TM, Devos D, Dexter DT, Duffen J, Federoff H, Fiske B, Foltynie T, Fox S, Greenamyre JT, Kieburtz K, Kordower JH, Krainc D, Matthews H, Moore DJ, Mursaleen L, Schwarzschild MA, Stott SRW, Sulzer D, Svenningsson P, Tanner CM, Carroll C, Simon DK, Brundin P. Wyse RK, et al. Among authors: moore dj. J Parkinsons Dis. 2024 Apr 5. doi: 10.3233/JPD-230363. Online ahead of print. J Parkinsons Dis. 2024. PMID: 38578902 Review.

2

Role for the ubiquitin-proteasome system in Parkinson's disease and other neurodegenerative brain amyloidoses.

Moore DJ, Dawson VL, Dawson TM. Moore DJ, et al. Neuromolecular Med. 2003;4(1-2):95-108. doi: 10.1385/NMM:4:1-2:95. Neuromolecular Med. 2003. PMID: 14528055 Review.

3

Molecular pathophysiology of Parkinson's disease.

Moore DJ, West AB, Dawson VL, Dawson TM. Moore DJ, et al. Annu Rev Neurosci. 2005;28:57-87. doi: 10.1146/annurev.neuro.28.061604.135718. Annu Rev Neurosci. 2005. PMID: 16022590 Review.

4

Value of genetic models in understanding the cause and mechanisms of Parkinson's disease.

Moore DJ, Dawson TM. Moore DJ, et al. Curr Neurol Neurosci Rep. 2008 Jul;8(4):288-96. doi: 10.1007/s11910-008-0045-7. Curr Neurol Neurosci Rep. 2008. PMID: 18590612 Free PMC article. Review.

5

Revelations and revolutions in the understanding of Parkinson's disease.

Dawson TM, Moore DJ, West AB. Dawson TM, et al. Among authors: moore dj. Biochim Biophys Acta. 2009 Jul;1792(7):585-6. doi: 10.1016/j.bbadis.2009.06.001. Biochim Biophys Acta. 2009. PMID: 19539178 Free article. No abstract available.

6

A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.

Moore DJ, Zhang L, Dawson TM, Dawson VL. Moore DJ, et al. J Neurochem. 2003 Dec;87(6):1558-67. doi: 10.1111/j.1471-4159.2003.02265.x. J Neurochem. 2003. PMID: 14713311 Free article.

7

Lessons from Drosophila models of DJ-1 deficiency.

Moore DJ, Dawson VL, Dawson TM. Moore DJ, et al. Sci Aging Knowledge Environ. 2006 Jan 11;2006(2):pe2. doi: 10.1126/sageke.2006.2.pe2. Sci Aging Knowledge Environ. 2006. PMID: 16407572 Review.

8

Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2.

Li X, Moore DJ, Xiong Y, Dawson TM, Dawson VL. Li X, et al. Among authors: moore dj. J Biol Chem. 2010 Sep 17;285(38):29569-76. doi: 10.1074/jbc.M110.127639. Epub 2010 Jul 1. J Biol Chem. 2010. PMID: 20595391 Free PMC article.

9

Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity.

Fernández B, Chittoor-Vinod VG, Kluss JH, Kelly K, Bryant N, Nguyen APT, Bukhari SA, Smith N, Lara Ordóñez AJ, Fdez E, Chartier-Harlin MC, Montine TJ, Wilson MA, Moore DJ, West AB, Cookson MR, Nichols RJ, Hilfiker S. Fernández B, et al. Among authors: moore dj. J Parkinsons Dis. 2022;12(5):1423-1447. doi: 10.3233/JPD-213128. J Parkinsons Dis. 2022. PMID: 35599495 Free PMC article.

10

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity.

West AB, Moore DJ, Biskup S, Bugayenko A, Smith WW, Ross CA, Dawson VL, Dawson TM. West AB, et al. Among authors: moore dj. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16842-7. doi: 10.1073/pnas.0507360102. Epub 2005 Nov 3. Proc Natl Acad Sci U S A. 2005. PMID: 16269541 Free PMC article.

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