Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

288 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Discovery of novel 1,2,4-triazole phenylalanine derivatives targeting an unexplored region within the interprotomer pocket of the HIV capsid protein.
Jiang X, Sharma PP, Rathi B, Ji X, Hu L, Gao Z, Kang D, Wang Z, Xie M, Xu S, Zhang X, De Clercq E, Cocklin S, Pannecouque C, Dick A, Liu X, Zhan P. Jiang X, et al. Among authors: sharma pp. J Med Virol. 2022 Dec;94(12):5975-5986. doi: 10.1002/jmv.28064. Epub 2022 Aug 18. J Med Virol. 2022. PMID: 35949003 Free PMC article.
Escaping from Flatland: Multiparameter Optimization Leads to the Discovery of Novel Tetrahydropyrido[4,3-d]pyrimidine Derivatives as Human Immunodeficiency Virus-1 Non-nucleoside Reverse Transcriptase Inhibitors with Superior Antiviral Activities against Non-nucleoside Reverse Transcriptase Inhibitor-Resistant Variants and Favorable Drug-like Profiles.
Wang Z, Sharma PP, Rathi B, Xie M, De Clercq E, Pannecouque C, Kang D, Zhan P, Liu X. Wang Z, et al. Among authors: sharma pp. J Med Chem. 2023 Jul 13;66(13):8643-8665. doi: 10.1021/acs.jmedchem.3c00275. Epub 2023 May 31. J Med Chem. 2023. PMID: 37255025
Computational study of novel inhibitory molecule, 1-(4-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus.
Sharma PP, Kumar S, Srivastava S, Srivastava M, Jee B, Gorobets NY, Kumar D, Kumar M, Asthana S, Zhang P, Poonam, Zoltner M, Rathi B. Sharma PP, et al. J Biomol Struct Dyn. 2022;40(20):10162-10180. doi: 10.1080/07391102.2021.1940281. Epub 2021 Jun 21. J Biomol Struct Dyn. 2022. PMID: 34151735
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure-Activity Relationship Studies.
Kumar S, Sharma PP, Shankar U, Kumar D, Joshi SK, Pena L, Durvasula R, Kumar A, Kempaiah P, Poonam, Rathi B. Kumar S, et al. Among authors: sharma pp. J Chem Inf Model. 2020 Dec 28;60(12):5754-5770. doi: 10.1021/acs.jcim.0c00326. Epub 2020 Jun 18. J Chem Inf Model. 2020. PMID: 32551639
Searching Anti-Zika Virus Activity in 1H-1,2,3-Triazole Based Compounds.
Dantas WM, de Oliveira VNM, Santos DAL, Seabra G, Sharma PP, Rathi B, Pena LJ, de Oliveira RN. Dantas WM, et al. Among authors: sharma pp. Molecules. 2021 Sep 28;26(19):5869. doi: 10.3390/molecules26195869. Molecules. 2021. PMID: 34641413 Free PMC article.
288 results