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Differences in neuroinflammation in people who started antiretroviral treatment during primary versus chronic HIV infection: an 18kDa Translocator protein (TSPO) positron emission tomography (PET) study.
Alagaratnam J, Thornhill JP, Fan Z, Vera JH, Underwood J, Hall R, Searle G, Owen D, Edison P, Fidler S, Winston A. Alagaratnam J, et al. Among authors: searle g. J Neurovirol. 2024 Apr 4. doi: 10.1007/s13365-024-01200-3. Online ahead of print. J Neurovirol. 2024. PMID: 38575831
Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599).
Mercier J, Bani M, Colson AO, Germani M, Lalla M, Plisson C, Huiban M, Searle G, Mathy FX, Nicholl R, Otoul C, Smit JW, van Asch V, Wagneur M, Maguire RP. Mercier J, et al. Among authors: searle g. Mol Imaging Biol. 2024 Apr;26(2):310-321. doi: 10.1007/s11307-023-01878-7. Epub 2023 Dec 18. Mol Imaging Biol. 2024. PMID: 38110790 Free PMC article. Clinical Trial.
A PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod.
Roussakis AA, Gennaro M, Gordon MF, Reilmann R, Borowsky B, Rynkowski G, Lao-Kaim NP, Papoutsou Z, Savola JM, Hayden MR, Owen DR, Kalk N, Lingford-Hughes A, Gunn RN, Searle G, Tabrizi SJ, Piccini P. Roussakis AA, et al. Among authors: searle g. Brain Commun. 2023 Apr 3;5(2):fcad084. doi: 10.1093/braincomms/fcad084. eCollection 2023. Brain Commun. 2023. PMID: 37020532 Free PMC article.
Brain Serotonin Release Is Reduced in Patients With Depression: A [11C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge.
Erritzoe D, Godlewska BR, Rizzo G, Searle GE, Agnorelli C, Lewis Y, Ashok AH, Colasanti A, Boura I, Farrell C, Parfitt H, Howes O, Passchier J, Gunn RN, Politis M, Nutt DJ, Cowen PJ, Knudsen GM, Rabiner EA. Erritzoe D, et al. Among authors: searle ge. Biol Psychiatry. 2023 Jun 15;93(12):1089-1098. doi: 10.1016/j.biopsych.2022.10.012. Epub 2022 Oct 29. Biol Psychiatry. 2023. PMID: 36635177
PET-BIDS, an extension to the brain imaging data structure for positron emission tomography.
Norgaard M, Matheson GJ, Hansen HD, Thomas A, Searle G, Rizzo G, Veronese M, Giacomel A, Yaqub M, Tonietto M, Funck T, Gillman A, Boniface H, Routier A, Dalenberg JR, Betthauser T, Feingold F, Markiewicz CJ, Gorgolewski KJ, Blair RW, Appelhoff S, Gau R, Salo T, Niso G, Pernet C, Phillips C, Oostenveld R, Gallezot JD, Carson RE, Knudsen GM, Innis RB, Ganz M. Norgaard M, et al. Among authors: searle g. Sci Data. 2022 Mar 2;9(1):65. doi: 10.1038/s41597-022-01164-1. Sci Data. 2022. PMID: 35236846 Free PMC article.
Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [11C]PHNO PET.
Rabiner EA, Uz T, Mansur A, Brown T, Chen G, Wu J, Atienza J, Schwarz AJ, Yin W, Lewis Y, Searle GE, Dennison JMTJ, Passchier J, Gunn RN, Tauscher J. Rabiner EA, et al. Among authors: searle ge. Neuropsychopharmacology. 2022 Jun;47(7):1405-1412. doi: 10.1038/s41386-021-01204-1. Epub 2021 Oct 21. Neuropsychopharmacology. 2022. PMID: 34675381 Free PMC article.
Adenosine A2A receptor in schizophrenia: an in vivo brain PET imaging study.
Marques TR, Natesan S, Rabiner EA, Searle GE, Gunn R, Howes OD, Kapur S. Marques TR, et al. Among authors: searle ge. Psychopharmacology (Berl). 2022 Nov;239(11):3439-3445. doi: 10.1007/s00213-021-05900-0. Epub 2021 Jun 26. Psychopharmacology (Berl). 2022. PMID: 34175983 Free PMC article.
146 results