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Page 1
Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endothelial colony forming cells.
Laan SNJ, de Boer S, Dirven RJ, van Moort I, Kuipers TB, Mei H, Bierings R, Eikenboom J; SYMPHONY consortium. Laan SNJ, et al. Among authors: van moort i. J Thromb Haemost. 2024 Apr 2:S1538-7836(24)00176-4. doi: 10.1016/j.jtha.2024.03.018. Online ahead of print. J Thromb Haemost. 2024. PMID: 38574861 Free article.
SYMPHONY consortium: Orchestrating personalized treatment for patients with bleeding disorders.
Cnossen MH, van Moort I, Reitsma SH, de Maat MPM, Schutgens REG, Urbanus RT, Lingsma HF, Mathot RAA, Gouw SC, Meijer K, Bredenoord AL, van der Graaf R, Fijnvandraat K, Meijer AB, van den Akker E, Bierings R, Eikenboom JCJ, van den Biggelaar M, de Haas M, Voorberg J, Leebeek FWG; SYMPHONY consortium. Cnossen MH, et al. Among authors: van moort i. J Thromb Haemost. 2022 Jun 2;20(9):2001-11. doi: 10.1111/jth.15778. Online ahead of print. J Thromb Haemost. 2022. PMID: 35652368 Free PMC article.
One piece of the puzzle: Population pharmacokinetics of FVIII during perioperative Haemate P® /Humate P® treatment in von Willebrand disease patients.
de Jager NCB, Bukkems LH, Heijdra JM, Hazendonk CHCAM, Fijnvandraat K, Meijer K, Eikenboom J, Laros-van Gorkom BAP, Leebeek FWG, Cnossen MH, Mathôt RAA; OPTI-CLOT group. de Jager NCB, et al. J Thromb Haemost. 2020 Feb;18(2):295-305. doi: 10.1111/jth.14652. Epub 2019 Oct 21. J Thromb Haemost. 2020. PMID: 31557387 Free PMC article.
Mutations in Neurobeachin-like 2 do not impact Weibel-Palade body biogenesis and von Willebrand factor secretion in gray platelet syndrome Endothelial Colony Forming Cells.
Kat M, van Moort I, Bürgisser PE, Kuijpers TW, Hofman M, Favier M, Favier R, Margadant C, Voorberg J, Bierings R. Kat M, et al. Among authors: van moort i. Res Pract Thromb Haemost. 2023 Feb 14;7(2):100086. doi: 10.1016/j.rpth.2023.100086. eCollection 2023 Feb. Res Pract Thromb Haemost. 2023. PMID: 36923710 Free PMC article.
von Willebrand Factor and Factor VIII Clearance in Perioperative Hemophilia A Patients.
van Moort I, Bukkems LH, Heijdra JM, Schutgens REG, Laros-van Gorkom BAP, Nieuwenhuizen L, van der Meer FJM, Fijnvandraat K, Ypma P, de Maat MPM, Leebeek FWG, Meijer K, Eikenboom J, Mathôt RAA, Cnossen MH; OPTI-CLOT Study Group. van Moort I, et al. Among authors: van der meer fjm. Thromb Haemost. 2020 Jul;120(7):1056-1065. doi: 10.1055/s-0040-1710591. Epub 2020 Jun 1. Thromb Haemost. 2020. PMID: 32480417 Clinical Trial.
Platelet degranulation and bleeding phenotype in a large cohort of Von Willebrand disease patients.
Swinkels M, Atiq F, Bürgisser PE, van Moort I, Meijer K, Eikenboom J, Fijnvandraat K, van Galen KPM, de Meris J, Schols SEM, van der Bom JG, Cnossen MH, Voorberg J, Leebeek FWG, Bierings R, Jansen AJG; WiN study group. Swinkels M, et al. Among authors: van moort i. Br J Haematol. 2022 May;197(4):497-501. doi: 10.1111/bjh.18145. Epub 2022 Mar 22. Br J Haematol. 2022. PMID: 36165954 Free PMC article.
Analysis of current perioperative management with Haemate® P/Humate P® in von Willebrand disease: Identifying the need for personalized treatment.
Hazendonk HCAM, Heijdra JM, de Jager NCB, Veerman HC, Boender J, van Moort I, Mathôt RAA, Meijer K, Laros-van Gorkom BAP, Eikenboom J, Fijnvandraat K, Leebeek FWG, Cnossen MH; “OPTI-CLOT” and “WIN” study group. Hazendonk HCAM, et al. Among authors: van moort i. Haemophilia. 2018 May;24(3):460-470. doi: 10.1111/hae.13451. Epub 2018 Mar 24. Haemophilia. 2018. PMID: 29573506
Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial): an open-label, multicentre, randomised, controlled trial.
van Moort I, Preijers T, Bukkems LH, Hazendonk HCAM, van der Bom JG, Laros-van Gorkom BAP, Beckers EAM, Nieuwenhuizen L, van der Meer FJM, Ypma P, Coppens M, Fijnvandraat K, Schutgens REG, Meijer K, Leebeek FWG, Mathôt RAA, Cnossen MH; OPTI-CLOT study group. van Moort I, et al. Among authors: van der meer fjm, van der bom jg. Lancet Haematol. 2021 Jul;8(7):e492-e502. doi: 10.1016/S2352-3026(21)00135-6. Lancet Haematol. 2021. PMID: 34171280 Clinical Trial.
Population pharmacokinetics of factor IX in hemophilia B patients undergoing surgery.
Preijers T, Hazendonk HCAM, Liesner R, Chowdary P, Driessens MHE, Hart D, Keeling D, Laros-van Gorkom BAP, van der Meer FJM, Meijer K, Fijnvandraat K, Leebeek FWG, Collins PW, Cnossen MH, Mathôt RAA; OPTI‐CLOT study group. Preijers T, et al. J Thromb Haemost. 2018 Nov;16(11):2196-2207. doi: 10.1111/jth.14292. Epub 2018 Oct 28. J Thromb Haemost. 2018. PMID: 30394056 Free article.
Cross-evaluation of Pharmacokinetic-Guided Dosing Tools for Factor VIII.
Preijers T, van Moort I, Fijnvandraat K, Leebeek FWG, Cnossen MH, Mathôt RAA; ‘OPTI-CLOT’ Study Group. Preijers T, et al. Among authors: van moort i. Thromb Haemost. 2018 Mar;118(3):514-525. doi: 10.1055/s-0038-1623531. Epub 2018 Mar 13. Thromb Haemost. 2018. PMID: 29534249
25 results