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A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.
Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. Huang T, et al. Among authors: nakano i. Nat Commun. 2016 Oct 4;7:12885. doi: 10.1038/ncomms12885. Nat Commun. 2016. PMID: 27698350 Free PMC article.
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy.
Bastola S, Pavlyukov MS, Yamashita D, Ghosh S, Cho H, Kagaya N, Zhang Z, Minata M, Lee Y, Sadahiro H, Yamaguchi S, Komarova S, Yang E, Markert J, Nabors LB, Bhat K, Lee J, Chen Q, Crossman DK, Shin-Ya K, Nam DH, Nakano I. Bastola S, et al. Among authors: nakano i. Nat Commun. 2020 Sep 16;11(1):4660. doi: 10.1038/s41467-020-18189-y. Nat Commun. 2020. PMID: 32938908 Free PMC article.
Senescence from glioma stem cell differentiation promotes tumor growth.
Ouchi R, Okabe S, Migita T, Nakano I, Seimiya H. Ouchi R, et al. Among authors: nakano i. Biochem Biophys Res Commun. 2016 Feb 5;470(2):275-281. doi: 10.1016/j.bbrc.2016.01.071. Epub 2016 Jan 14. Biochem Biophys Res Commun. 2016. PMID: 26775840 Free PMC article.
A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Jun HJ, Appleman VA, Wu HJ, Rose CM, Pineda JJ, Yeo AT, Delcuze B, Lee C, Gyuris A, Zhu H, Woolfenden S, Bronisz A, Nakano I, Chiocca EA, Bronson RT, Ligon KL, Sarkaria JN, Gygi SP, Michor F, Mitchison TJ, Charest A. Jun HJ, et al. Among authors: nakano i. Nat Commun. 2018 Aug 6;9(1):3116. doi: 10.1038/s41467-018-05036-4. Nat Commun. 2018. PMID: 30082792 Free PMC article.
Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells.
Larionova TD, Bastola S, Aksinina TE, Anufrieva KS, Wang J, Shender VO, Andreev DE, Kovalenko TF, Arapidi GP, Shnaider PV, Kazakova AN, Latyshev YA, Tatarskiy VV, Shtil AA, Moreau P, Giraud F, Li C, Wang Y, Rubtsova MP, Dontsova OA, Condro M, Ellingson BM, Shakhparonov MI, Kornblum HI, Nakano I, Pavlyukov MS. Larionova TD, et al. Among authors: nakano i. Nat Cell Biol. 2022 Oct;24(10):1541-1557. doi: 10.1038/s41556-022-00994-w. Epub 2022 Oct 3. Nat Cell Biol. 2022. PMID: 36192632 Free PMC article.
1,207 results