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Natural Amino Acid-Bearing Carbamate Prodrugs of Daidzein Increase Water Solubility and Improve Phase II Metabolic Stability for Enhanced Oral Bioavailability.
Li Y, Liu X, Lu F, Li H, Zhang J, Zhang Y, Li W, Wang W, Yang M, Ma Z, Zhang H, Zhou X, Xu Y, He Z, Sun J, Zhang T, Jiang Q. Li Y, et al. Among authors: jiang q. J Agric Food Chem. 2024 Apr 17;72(15):8618-8631. doi: 10.1021/acs.jafc.4c01251. Epub 2024 Apr 3. J Agric Food Chem. 2024. PMID: 38569082
A rapid ultra high performance liquid chromatography-tandem mass spectrometry method for the quantification of daidzein, its valine carbamate prodrug, and glucuronide in rat plasma samples: Comparison of the pharmacokinetic behavior of daidzine valine carbamate prodrugs.
Li Y, Lu F, Zhang Y, Liu X, Lin L, Jiang Q, Zhang T. Li Y, et al. Among authors: jiang q. J Sep Sci. 2021 Oct;44(19):3691-3699. doi: 10.1002/jssc.202100331. Epub 2021 Aug 16. J Sep Sci. 2021. PMID: 34347375
Modulation of Naturally Occurring Linear Dipeptide Chirality to Reduce the Affinity for Oligopeptide Transporter 1 and Increase Intestinal Stability for an Enhanced Colon-Targeting Effect in the Treatment of Inflammatory Bowel Disease: An Application of trans-4-l-Hydroxyprolyl-l-serine.
Jiang Q, Xu Q, Wang Y, Li P, Zhang Y, Wang Y, Sun J, Zhang T, He Z. Jiang Q, et al. J Med Chem. 2022 Mar 24;65(6):4565-4577. doi: 10.1021/acs.jmedchem.1c01276. Epub 2021 Nov 29. J Med Chem. 2022. PMID: 34842428
Ultra-high performance supercritical fluid chromatography-tandem mass spectrometry method for simultaneous determination of atorvastatin, 2-hydroxy atorvastatin, and tangeretin in rat plasma and its application to the pharmacokinetic study.
Li W, Wang S, Wang W, Gong L, Ni D, Li Y, Wu W, Zhang Y, Xu X, Jiang Q, Zhang J, Zhang T. Li W, et al. Among authors: jiang q. J Sep Sci. 2022 Nov;45(21):3985-3994. doi: 10.1002/jssc.202200185. J Sep Sci. 2022. PMID: 36030366
Bioactivatable Pseudotripeptidization of Cyclic Dipeptides To Increase the Affinity toward Oligopeptide Transporter 1 for Enhanced Oral Absorption: An Application to Cyclo(l-Hyp-l-Ser) (JBP485).
Jiang Q, Zhang J, Tong P, Gao Y, Lv Y, Wang C, Luo M, Sun M, Wang J, Feng Y, Cao L, Wang G, Wang Y, Kan Q, Zhang T, Wang Y, Liu K, Sun J, He Z. Jiang Q, et al. J Med Chem. 2019 Sep 12;62(17):7708-7721. doi: 10.1021/acs.jmedchem.9b00358. Epub 2019 Sep 3. J Med Chem. 2019. PMID: 31393124
8,824 results