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Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations.
Heffernan J, Garcia Gonzalez RA, Mahamkali V, McCubbin T, Daygon D, Liu L, Palfreyman R, Harris A, Koepke M, Valgepea K, Nielsen LK, Marcellin E. Heffernan J, et al. Among authors: palfreyman r. Microb Biotechnol. 2024 Apr;17(4):e14452. doi: 10.1111/1751-7915.14452. Microb Biotechnol. 2024. PMID: 38568755 Free PMC article.
Maintenance of ATP Homeostasis Triggers Metabolic Shifts in Gas-Fermenting Acetogens.
Valgepea K, de Souza Pinto Lemgruber R, Meaghan K, Palfreyman RW, Abdalla T, Heijstra BD, Behrendorff JB, Tappel R, Köpke M, Simpson SD, Nielsen LK, Marcellin E. Valgepea K, et al. Among authors: palfreyman rw. Cell Syst. 2017 May 24;4(5):505-515.e5. doi: 10.1016/j.cels.2017.04.008. Epub 2017 May 17. Cell Syst. 2017. PMID: 28527885 Free article.
Systems-level engineering and characterisation of Clostridium autoethanogenum through heterologous production of poly-3-hydroxybutyrate (PHB).
de Souza Pinto Lemgruber R, Valgepea K, Tappel R, Behrendorff JB, Palfreyman RW, Plan M, Hodson MP, Simpson SD, Nielsen LK, Köpke M, Marcellin E. de Souza Pinto Lemgruber R, et al. Among authors: palfreyman rw. Metab Eng. 2019 May;53:14-23. doi: 10.1016/j.ymben.2019.01.003. Epub 2019 Jan 11. Metab Eng. 2019. PMID: 30641139
A TetR-Family Protein (CAETHG_0459) Activates Transcription From a New Promoter Motif Associated With Essential Genes for Autotrophic Growth in Acetogens.
de Souza Pinto Lemgruber R, Valgepea K, Gonzalez Garcia RA, de Bakker C, Palfreyman RW, Tappel R, Köpke M, Simpson SD, Nielsen LK, Marcellin E. de Souza Pinto Lemgruber R, et al. Among authors: palfreyman rw. Front Microbiol. 2019 Nov 15;10:2549. doi: 10.3389/fmicb.2019.02549. eCollection 2019. Front Microbiol. 2019. PMID: 31803150 Free PMC article.
Time-course transcriptomics reveals that amino acids catabolism plays a key role in toxinogenesis and morphology in Clostridium tetani.
Orellana CA, Zaragoza NE, Licona-Cassani C, Palfreyman RW, Cowie N, Moonen G, Moutafis G, Power J, Nielsen LK, Marcellin E. Orellana CA, et al. Among authors: palfreyman rw. J Ind Microbiol Biotechnol. 2020 Dec;47(12):1059-1073. doi: 10.1007/s10295-020-02330-3. Epub 2020 Nov 11. J Ind Microbiol Biotechnol. 2020. PMID: 33175241
28 results