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Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch.
Gretarsson KH, Abini-Agbomson S, Gloor SL, Weinberg DN, McCuiston JL, Kumary VUS, Hickman AR, Sahu V, Lee R, Xu X, Lipieta N, Flashner S, Adeleke OA, Popova IK, Taylor HF, Noll K, Windham CL, Maryanski DN, Venters BJ, Nakagawa H, Keogh MC, Armache KJ, Lu C. Gretarsson KH, et al. Among authors: flashner s. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585588. doi: 10.1101/2024.03.18.585588. bioRxiv. 2024. PMID: 38562823 Free PMC article. Preprint.
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids.
Flashner S, Martin C, Matsuura N, Shimonosono M, Tomita Y, Morimoto M, Okolo O, Yu VX, Parikh AS, Klein-Szanto AJP, Yan K, Gabre JT, Lu C, Momen-Heravi F, Rustgi AK, Nakagawa H. Flashner S, et al. J Vis Exp. 2022 Dec 23;(190):10.3791/64676. doi: 10.3791/64676. J Vis Exp. 2022. PMID: 36622034 Free PMC article.
ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment.
Flashner S, Shimonosono M, Tomita Y, Matsuura N, Ohashi S, Muto M, Klein-Szanto AJ, Alan Diehl J, Chen CH, Mochly-Rosen D, Weinberg KI, Nakagawa H. Flashner S, et al. Carcinogenesis. 2024 Feb 12;45(1-2):95-106. doi: 10.1093/carcin/bgad085. Carcinogenesis. 2024. PMID: 37978873
Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy.
Shimonosono M, Tanaka K, Flashner S, Takada S, Matsuura N, Tomita Y, Sachdeva UM, Noguchi E, Sangwan V, Ferri L, Momen-Heravi F, Yoon AJ, Klein-Szanto AJ, Diehl JA, Nakagawa H. Shimonosono M, et al. Among authors: flashner s. Biomolecules. 2021 Oct 7;11(10):1479. doi: 10.3390/biom11101479. Biomolecules. 2021. PMID: 34680112 Free PMC article.
21 results