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Biomolecular condensates form spatially inhomogeneous network fluids.
Dar F, Cohen SR, Mitrea DM, Phillips AH, Nagy G, Leite WC, Stanley CB, Choi JM, Kriwacki RW, Pappu RV. Dar F, et al. Among authors: pappu rv. Nat Commun. 2024 Apr 22;15(1):3413. doi: 10.1038/s41467-024-47602-z. Nat Commun. 2024. PMID: 38649740 Free PMC article.
Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient.
King MR, Ruff KM, Lin AZ, Pant A, Farag M, Lalmansingh JM, Wu T, Fossat MJ, Ouyang W, Lew MD, Lundberg E, Vahey MD, Pappu RV. King MR, et al. Among authors: pappu rv. Cell. 2024 Apr 11;187(8):1889-1906.e24. doi: 10.1016/j.cell.2024.02.029. Epub 2024 Mar 18. Cell. 2024. PMID: 38503281 Free article.
Metastable condensates suppress conversion to amyloid fibrils.
Das T, Zaidi F, Farag M, Ruff KM, Messing J, Taylor JP, Pappu RV, Mittag T. Das T, et al. Among authors: pappu rv. bioRxiv [Preprint]. 2024 Mar 3:2024.02.28.582569. doi: 10.1101/2024.02.28.582569. bioRxiv. 2024. PMID: 38464104 Free PMC article. Preprint.
Emergent microenvironments of nucleoli.
King MR, Ruff KM, Pappu RV. King MR, et al. Among authors: pappu rv. Nucleus. 2024 Dec;15(1):2319957. doi: 10.1080/19491034.2024.2319957. Epub 2024 Mar 5. Nucleus. 2024. PMID: 38443761 Free PMC article. Review.
Dynamical control enables the formation of demixed biomolecular condensates.
Lin AZ, Ruff KM, Dar F, Jalihal A, King MR, Lalmansingh JM, Posey AE, Erkamp NA, Seim I, Gladfelter AS, Pappu RV. Lin AZ, et al. Among authors: pappu rv. Nat Commun. 2023 Nov 24;14(1):7678. doi: 10.1038/s41467-023-43489-4. Nat Commun. 2023. PMID: 37996438 Free PMC article.
182 results