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A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with Early Alzheimer's Disease.
Galasko D, Farlow MR, Lucey BP, Honig LS, Elbert D, Bateman R, Momper J, Thomas R, Rissman RA, Pa J, Aslanyan V, Balasubramanian A, West T, Maccecchini M, Feldman HH. Galasko D, et al. Among authors: elbert d. medRxiv [Preprint]. 2024 Mar 22:2024.03.20.24304638. doi: 10.1101/2024.03.20.24304638. medRxiv. 2024. PMID: 38562783 Free PMC article. Preprint.
SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases.
Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, Wray S, Miller TM, Elbert DL, Zetterberg H, Fox NC, Bateman RJ. Paterson RW, et al. Among authors: elbert dl. Nat Rev Neurol. 2019 Jul;15(7):419-427. doi: 10.1038/s41582-019-0222-0. Epub 2019 Jun 20. Nat Rev Neurol. 2019. PMID: 31222062 Free PMC article. Review.
Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracer In Vivo and Exhibit Nanoscale Heterogeneity.
Wildburger NC, Gyngard F, Guillermier C, Patterson BW, Elbert D, Mawuenyega KG, Schneider T, Green K, Roth R, Schmidt RE, Cairns NJ, Benzinger TLS, Steinhauser ML, Bateman RJ. Wildburger NC, et al. Among authors: elbert d. Front Neurol. 2018 Mar 22;9:169. doi: 10.3389/fneur.2018.00169. eCollection 2018. Front Neurol. 2018. PMID: 29623063 Free PMC article.
Reply to "Excess amyloid beta can be degraded in healthy humans".
Lucey BP, Hicks TJ, Elbert DL, Ovod V, Mawuenyega KG, Morris JC, Bateman RJ. Lucey BP, et al. Among authors: elbert dl. Ann Neurol. 2018 Mar;83(3):650-651. doi: 10.1002/ana.25185. Epub 2018 Mar 3. Ann Neurol. 2018. PMID: 29457845 No abstract available.
Effect of sleep on overnight cerebrospinal fluid amyloid β kinetics.
Lucey BP, Hicks TJ, McLeland JS, Toedebusch CD, Boyd J, Elbert DL, Patterson BW, Baty J, Morris JC, Ovod V, Mawuenyega KG, Bateman RJ. Lucey BP, et al. Among authors: elbert dl. Ann Neurol. 2018 Jan;83(1):197-204. doi: 10.1002/ana.25117. Ann Neurol. 2018. PMID: 29220873 Free PMC article.
56 results