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CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality.
Tien JC, Chang Y, Zhang Y, Chou J, Cheng Y, Wang X, Yang J, Mannan R, Shah P, Wang XM, Todd AJ, Eyunni S, Cheng C, Rebernick RJ, Xiao L, Bao Y, Neiswender J, Brough R, Pettitt SJ, Cao X, Miner SJ, Zhou L, Wu YM, Labanca E, Wang Y, Parolia A, Cieslik M, Robinson DR, Wang Z, Feng FY, Lord CJ, Ding K, Chinnaiyan AM. Tien JC, et al. Among authors: bao y. bioRxiv [Preprint]. 2024 Mar 21:2024.03.20.585990. doi: 10.1101/2024.03.20.585990. bioRxiv. 2024. PMID: 38562774 Free PMC article. Preprint.
PIKfyve controls dendritic cell function and tumor immunity.
Choi JE, Qiao Y, Kryczek I, Yu J, Gurkan J, Bao Y, Gondal M, Tien JC, Maj T, Yazdani S, Parolia A, Xia H, Zhou J, Wei S, Grove S, Vatan L, Lin H, Li G, Zheng Y, Zhang Y, Cao X, Su F, Wang R, He T, Cieslik M, Green MD, Zou W, Chinnaiyan AM. Choi JE, et al. Among authors: bao y. bioRxiv [Preprint]. 2024 Mar 2:2024.02.28.582543. doi: 10.1101/2024.02.28.582543. bioRxiv. 2024. PMID: 38464258 Free PMC article. Preprint.
Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer.
Cheng C, Hu J, Mannan R, Bhattacharyya R, Rossiter NJ, Magnuson B, Wisniewski JP, Zheng Y, Xiao L, Li C, Awad D, He T, Bao Y, Zhang Y, Cao X, Wang Z, Mehra R, Morlacchi P, Sahai V, di Magliano MP, Shah YM, Ding K, Qiao Y, Lyssiotis CA, Chinnaiyan AM. Cheng C, et al. Among authors: bao y. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585580. doi: 10.1101/2024.03.18.585580. bioRxiv. 2024. PMID: 38562800 Free PMC article. Preprint.
Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy.
Bao Y, Qiao Y, Choi JE, Zhang Y, Mannan R, Cheng C, He T, Zheng Y, Yu J, Gondal M, Cruz G, Grove S, Cao X, Su F, Wang R, Chang Y, Kryczek I, Cieslik M, Green MD, Zou W, Chinnaiyan AM. Bao Y, et al. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2314416120. doi: 10.1073/pnas.2314416120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011559 Free PMC article.
Brain abnormalities in survivors of COVID-19 after 2-year recovery: a functional MRI study.
Zhao Y, Liang Q, Jiang Z, Mei H, Zeng N, Su S, Wu S, Ge Y, Li P, Lin X, Yuan K, Shi L, Yan W, Liu X, Sun J, Liu W, van Wingen G, Gao Y, Tan Y, Hong Y, Lu Y, Wu P, Zhang X, Wang Y, Shi J, Wang Y, Lu L, Li X, Bao Y. Zhao Y, et al. Among authors: bao y. Lancet Reg Health West Pac. 2024 May 9;47:101086. doi: 10.1016/j.lanwpc.2024.101086. eCollection 2024 Jun. Lancet Reg Health West Pac. 2024. PMID: 38774424 Free PMC article.
6,544 results