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A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice.
Cao S, Budina E, Raczy MM, Solanki A, Nguyen M, Beckman TN, Reda JW, Hultgren K, Ang PS, Slezak AJ, Hesser LA, Alpar AT, Refvik KC, Shores LS, Pillai I, Wallace RP, Dhar A, Watkins EA, Hubbell JA. Cao S, et al. Among authors: hultgren k. Nat Biomed Eng. 2024 Apr 1. doi: 10.1038/s41551-024-01190-x. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38561491
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity.
Kang S, Mansurov A, Kurtanich T, Chun HR, Slezak AJ, Volpatti LR, Chang K, Wang T, Alpar AT, Refvik KC, Hansen OI, Borjas GJ, Shim HN, Hultgren KT, Gomes S, Solanki A, Ishihara J, Swartz MA, Hubbell JA. Kang S, et al. Among authors: hultgren kt. Sci Adv. 2023 Dec;9(48):eadh9879. doi: 10.1126/sciadv.adh9879. Epub 2023 Nov 29. Sci Adv. 2023. PMID: 38019919 Free PMC article.
Climate drives the geography of marine consumption by changing predator communities.
Whalen MA, Whippo RDB, Stachowicz JJ, York PH, Aiello E, Alcoverro T, Altieri AH, Benedetti-Cecchi L, Bertolini C, Bresch M, Bulleri F, Carnell PE, Cimon S, Connolly RM, Cusson M, Diskin MS, D'Souza E, Flores AAV, Fodrie FJ, Galloway AWE, Gaskins LC, Graham OJ, Hanley TC, Henderson CJ, Hereu CM, Hessing-Lewis M, Hovel KA, Hughes BB, Hughes AR, Hultgren KM, Jänes H, Janiak DS, Johnston LN, Jorgensen P, Kelaher BP, Kruschel C, Lanham BS, Lee KS, Lefcheck JS, Lozano-Álvarez E, Macreadie PI, Monteith ZL, O'Connor NE, Olds AD, O'Leary JK, Patrick CJ, Pino O, Poore AGB, Rasheed MA, Raymond WW, Reiss K, Rhoades OK, Robinson MT, Ross PG, Rossi F, Schlacher TA, Seemann J, Silliman BR, Smee DL, Thiel M, Unsworth RKF, van Tussenbroek BI, Vergés A, Yeager ME, Yednock BK, Ziegler SL, Duffy JE. Whalen MA, et al. Among authors: hultgren km. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28160-28166. doi: 10.1073/pnas.2005255117. Epub 2020 Oct 26. Proc Natl Acad Sci U S A. 2020. PMID: 33106409 Free PMC article.
32 results