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Sialic Acid Mediated Endothelial and Hepatic Uptake: A Mechanism based Mathematic Model Elucidating the Complex Pharmacokinetics and Pharmacodynamics of Efmarodocokin Alfa, a Variably Glycosylated Fusion Protein.
Tao X, Sukumaran S, Sperinde G, Liu C, Beardsley MI, Day P, Kalo M, Ayewoh E, Cai H, Wang Y, Jun I, Hirst K, Nguyen V, Chung S, Lee D, Lekkerkerker A, Stefanich E. Tao X, et al. Among authors: kalo m. J Pharm Sci. 2024 Mar 30:S0022-3549(24)00100-X. doi: 10.1016/j.xphs.2024.03.016. Online ahead of print. J Pharm Sci. 2024. PMID: 38561054 Free article.
Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial.
Waters M, McKinnell JA, Kalil AC, Martin GS, Buchman TG, Theess W, Yang X, Lekkerkerker AN, Staton T, Rosenberger CM, Pappu R, Wang Y, Zhang W, Brooks L, Cheung D, Galanter J, Chen H, Mohan D, Peck MC; COVID-astegolimab-interleukin (IL) (COVASTIL) Study Group. Waters M, et al. Crit Care Med. 2023 Jan 1;51(1):103-116. doi: 10.1097/CCM.0000000000005716. Epub 2022 Nov 14. Crit Care Med. 2023. PMID: 36519984 Free PMC article. Clinical Trial.
Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism.
Bissinger R, Nemkov T, D'Alessandro A, Grau M, Dietz T, Bohnert BN, Essigke D, Wörn M, Schaefer L, Xiao M, Beirne JM, Kalo MZ, Schork A, Bakchoul T, Omage K, Kong L, Gonzalez-Menendez I, Quintanilla-Martinez L, Fehrenbacher B, Schaller M, Dhariwal A, Birkenfeld AL, Grahammer F, Qadri SM, Artunc F. Bissinger R, et al. Among authors: kalo mz. Kidney Int. 2021 Dec;100(6):1227-1239. doi: 10.1016/j.kint.2021.08.024. Epub 2021 Sep 16. Kidney Int. 2021. PMID: 34537228 Free article.
Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice.
Bohnert BN, Gonzalez-Menendez I, Dörffel T, Schneider JC, Xiao M, Janessa A, Kalo MZ, Fehrenbacher B, Schaller M, Casadei N, Amann K, Daniel C, Birkenfeld AL, Grahammer F, Izem L, Plow EF, Quintanilla-Martinez L, Artunc F. Bohnert BN, et al. Among authors: kalo mz. Dis Model Mech. 2021 Sep 1;14(9):dmm049038. doi: 10.1242/dmm.049038. Epub 2021 Sep 15. Dis Model Mech. 2021. PMID: 34423816 Free PMC article.
Experimental nephrotic syndrome leads to proteolytic activation of the epithelial Na+ channel in the mouse kidney.
Bohnert BN, Essigke D, Janessa A, Schneider JC, Wörn M, Kalo MZ, Xiao M, Kong L, Omage K, Hennenlotter J, Amend B, Birkenfeld AL, Artunc F. Bohnert BN, et al. Among authors: kalo mz. Am J Physiol Renal Physiol. 2021 Oct 1;321(4):F480-F493. doi: 10.1152/ajprenal.00199.2021. Epub 2021 Aug 23. Am J Physiol Renal Physiol. 2021. PMID: 34423678 Free article.
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