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Neurobehavioral dysfunction in a mouse model of Down syndrome: upregulation of cystathionine β-synthase, H2S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy.
Geroscience. 2024 Apr 1. doi: 10.1007/s11357-024-01146-8. Online ahead of print.
Geroscience. 2024.
PMID: 38558215
Methanethiol: A Scent Mark of Dysregulated Sulfur Metabolism in Cancer.
Philipp TM, Scheller AS, Krafczyk N, Klotz LO, Steinbrenner H.
Philipp TM, et al.
Antioxidants (Basel). 2023 Sep 19;12(9):1780. doi: 10.3390/antiox12091780.
Antioxidants (Basel). 2023.
PMID: 37760083
Free PMC article.
Review.
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Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase.
Philipp TM, Gernoth L, Will A, Schwarz M, Ohse VA, Kipp AP, Steinbrenner H, Klotz LO.
Philipp TM, et al.
Redox Biol. 2023 Sep;65:102807. doi: 10.1016/j.redox.2023.102807. Epub 2023 Jul 4.
Redox Biol. 2023.
PMID: 37437449
Free PMC article.
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Altered Capacity for H2S Production during the Spontaneous Differentiation of Caco-2 Cells to Colonocytes Due to Reciprocal Regulation of CBS and SELENBP1.
Scheller AS, Philipp TM, Klotz LO, Steinbrenner H.
Scheller AS, et al. Among authors: philipp tm.
Antioxidants (Basel). 2022 Sep 30;11(10):1957. doi: 10.3390/antiox11101957.
Antioxidants (Basel). 2022.
PMID: 36290680
Free PMC article.
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SEMO-1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro-aging factor conferring selective stress resistance.
Philipp TM, Gong W, Köhnlein K, Ohse VA, Müller FI, Priebs J, Steinbrenner H, Klotz LO.
Philipp TM, et al.
Biofactors. 2022 May;48(3):699-706. doi: 10.1002/biof.1836. Epub 2022 Mar 22.
Biofactors. 2022.
PMID: 35316559
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A coupled enzyme assay for detection of selenium-binding protein 1 (SELENBP1) methanethiol oxidase (MTO) activity in mature enterocytes.
Philipp TM, Will A, Richter H, Winterhalter PR, Pohnert G, Steinbrenner H, Klotz LO.
Philipp TM, et al.
Redox Biol. 2021 Jul;43:101972. doi: 10.1016/j.redox.2021.101972. Epub 2021 Apr 15.
Redox Biol. 2021.
PMID: 33901808
Free PMC article.
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