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OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage.
Tsvilovskyy V, Ottenheijm R, Kriebs U, Schütz A, Diakopoulos KN, Jha A, Bildl W, Wirth A, Böck J, Jaślan D, Ferro I, Taberner FJ, Kalinina O, Hildebrand S, Wissenbach U, Weissgerber P, Vogt D, Eberhagen C, Mannebach S, Berlin M, Kuryshev V, Schumacher D, Philippaert K, Camacho-Londoño JE, Mathar I, Dieterich C, Klugbauer N, Biel M, Wahl-Schott C, Lipp P, Flockerzi V, Zischka H, Algül H, Lechner SG, Lesina M, Grimm C, Fakler B, Schulte U, Muallem S, Freichel M. Tsvilovskyy V, et al. Among authors: taberner fj. J Clin Invest. 2024 Apr 1;134(7):e169428. doi: 10.1172/JCI169428. J Clin Invest. 2024. PMID: 38557489 Free PMC article.
Structure-guided examination of the mechanogating mechanism of PIEZO2.
Taberner FJ, Prato V, Schaefer I, Schrenk-Siemens K, Heppenstall PA, Lechner SG. Taberner FJ, et al. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14260-14269. doi: 10.1073/pnas.1905985116. Epub 2019 Jun 24. Proc Natl Acad Sci U S A. 2019. PMID: 31235572 Free PMC article.
Neuropathic pain caused by miswiring and abnormal end organ targeting.
Gangadharan V, Zheng H, Taberner FJ, Landry J, Nees TA, Pistolic J, Agarwal N, Männich D, Benes V, Helmstaedter M, Ommer B, Lechner SG, Kuner T, Kuner R. Gangadharan V, et al. Among authors: taberner fj. Nature. 2022 Jun;606(7912):137-145. doi: 10.1038/s41586-022-04777-z. Epub 2022 May 25. Nature. 2022. PMID: 35614217 Free PMC article.
SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes.
Agarwal N, Taberner FJ, Rangel Rojas D, Moroni M, Omberbasic D, Njoo C, Andrieux A, Gupta P, Bali KK, Herpel E, Faghihi F, Fleming T, Dejean A, Lechner SG, Nawroth PP, Lewin GR, Kuner R. Agarwal N, et al. Among authors: taberner fj. Neuron. 2020 Sep 23;107(6):1141-1159.e7. doi: 10.1016/j.neuron.2020.06.037. Epub 2020 Jul 30. Neuron. 2020. PMID: 32735781 Free article.
Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
Nees TA, Wang N, Adamek P, Zeitzschel N, Verkest C, La Porta C, Schaefer I, Virnich J, Balkaya S, Prato V, Morelli C, Begay V, Lee YJ, Tappe-Theodor A, Lewin GR, Heppenstall PA, Taberner FJ, Lechner SG. Nees TA, et al. Among authors: taberner fj. Nat Commun. 2023 Apr 5;14(1):1899. doi: 10.1038/s41467-023-37602-w. Nat Commun. 2023. PMID: 37019973 Free PMC article.
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