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Preclinical evaluation of the SARS-CoV-2 Mpro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir.
Chen X, Huang X, Ma Q, Kuzmič P, Zhou B, Zhang S, Chen J, Xu J, Liu B, Jiang H, Zhang W, Yang C, Wu S, Huang J, Li H, Long C, Zhao X, Xu H, Sheng Y, Guo Y, Niu C, Xue L, Xu Y, Liu J, Zhang T, Spencer J, Zhu Z, Deng W, Chen X, Chen SH, Zhong N, Xiong X, Yang Z. Chen X, et al. Among authors: zhang s, zhang w, zhang t. Nat Microbiol. 2024 Apr;9(4):1075-1088. doi: 10.1038/s41564-024-01618-9. Epub 2024 Mar 29. Nat Microbiol. 2024. PMID: 38553607 Free PMC article.
Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China.
Hameed HA, Tan Y, Islam MM, Lu Z, Chhotaray C, Wang S, Liu Z, Fang C, Tan S, Yew WW, Zhong N, Liu J, Zhang T. Hameed HA, et al. Among authors: zhang t. Infect Drug Resist. 2020 Jan 22;13:217-227. doi: 10.2147/IDR.S230774. eCollection 2020. Infect Drug Resist. 2020. PMID: 32158237 Free PMC article.
A recombinant selective drug-resistant M. bovis BCG enhances the bactericidal activity of a second-line anti-tuberculosis regimen.
Chiwala G, Liu Z, Mugweru JN, Wang B, Khan SA, Bate PNN, Yusuf B, Hameed HMA, Fang C, Tan Y, Guan P, Hu J, Tan S, Liu J, Zhong N, Zhang T. Chiwala G, et al. Among authors: zhang t. Biomed Pharmacother. 2021 Oct;142:112047. doi: 10.1016/j.biopha.2021.112047. Epub 2021 Aug 21. Biomed Pharmacother. 2021. PMID: 34426260 Free article.
Arabinosyltransferase C Mediates Multiple Drugs Intrinsic Resistance by Altering Cell Envelope Permeability in Mycobacterium abscessus.
Wang S, Cai X, Yu W, Zeng S, Zhang J, Guo L, Gao Y, Lu Z, Hameed HMA, Fang C, Tian X, Yusuf B, Chhotaray C, Alam MDS, Zhang B, Ge H, Maslov DA, Cook GM, Peng J, Lin Y, Zhong N, Zhang G, Zhang T. Wang S, et al. Among authors: zhang b, zhang g, zhang t, zhang j. Microbiol Spectr. 2022 Aug 31;10(4):e0276321. doi: 10.1128/spectrum.02763-21. Epub 2022 Aug 10. Microbiol Spectr. 2022. PMID: 35946941 Free PMC article.
Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China.
Hameed HMA, Fang C, Liu Z, Ju Y, Han X, Gao Y, Wang S, Chiwala G, Tan Y, Guan P, Hu J, Xiong X, Peng J, Lin Y, Hussain M, Zhong N, Maslov DA, Cook GM, Liu J, Zhang T. Hameed HMA, et al. Among authors: zhang t. Infect Drug Resist. 2022 Sep 27;15:5655-5666. doi: 10.2147/IDR.S375869. eCollection 2022. Infect Drug Resist. 2022. PMID: 36193294 Free PMC article.
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