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HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution.
Kuo FC, Neville MJ, Sabaratnam R, Wesolowska-Andersen A, Phillips D, Wittemans LBL, van Dam AD, Loh NY, Todorčević M, Denton N, Kentistou KA, Joshi PK, Christodoulides C, Langenberg C, Collas P, Karpe F, Pinnick KE. Kuo FC, et al. Among authors: pinnick ke. Cell Rep. 2022 Jul 26;40(4):111136. doi: 10.1016/j.celrep.2022.111136. Cell Rep. 2022. PMID: 35905723 Free PMC article.
Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis.
Gunn PJ, Pramfalk C, Millar V, Cornfield T, Hutchinson M, Johnson EM, Nagarajan SR, Troncoso-Rey P, Mithen RF, Pinnick KE, Traka MH, Green CJ, Hodson L. Gunn PJ, et al. Among authors: pinnick ke. Physiol Rep. 2020 Jul;8(13):e14482. doi: 10.14814/phy2.14482. Physiol Rep. 2020. PMID: 32643289 Free PMC article.
RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro.
Loh NY, Minchin JEN, Pinnick KE, Verma M, Todorčević M, Denton N, Moustafa JE, Kemp JP, Gregson CL, Evans DM, Neville MJ, Small KS, McCarthy MI, Mahajan A, Rawls JF, Karpe F, Christodoulides C. Loh NY, et al. Among authors: pinnick ke. Nat Commun. 2020 Jun 3;11(1):2797. doi: 10.1038/s41467-020-16592-z. Nat Commun. 2020. PMID: 32493999 Free PMC article.
Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, English R, Adams RF, Frezza C, Buffa FM, Karpe F, Harris AL. Lord SR, et al. Among authors: pinnick ke. Br J Cancer. 2020 Jan;122(2):258-265. doi: 10.1038/s41416-019-0665-5. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819193 Free PMC article. Clinical Trial.
Bone morphogenetic protein 2 is a depot-specific regulator of human adipogenesis.
Denton NF, Eghleilib M, Al-Sharifi S, Todorčević M, Neville MJ, Loh N, Drakesmith A, Karpe F, Pinnick KE. Denton NF, et al. Among authors: pinnick ke. Int J Obes (Lond). 2019 Dec;43(12):2458-2468. doi: 10.1038/s41366-019-0421-1. Epub 2019 Jul 19. Int J Obes (Lond). 2019. PMID: 31324879 Free PMC article.
24 results