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MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis.
Phadnis VV, Snider J, Varadharajan V, Ramachandiran I, Deik AA, Lai ZW, Kunchok T, Eaton EN, Sebastiany C, Lyakisheva A, Vaccaro KD, Allen J, Yao Z, Wong V, Geng B, Weiskopf K, Clish CB, Brown JM, Stagljar I, Weinberg RA, Henry WS. Phadnis VV, et al. Among authors: weinberg ra. Cell Rep. 2023 Sep 26;42(9):113023. doi: 10.1016/j.celrep.2023.113023. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37691145 Free PMC article.
Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer.
Galhenage P, Zhou Y, Perry E, Loc B, Fietz K, Iyer S, Reinhardt F, Da Silva T, Botchkarev V, Chen J, Crum CP, Weinberg RA, Pathania S. Galhenage P, et al. Among authors: weinberg ra. Cell Rep. 2023 Oct 31;42(10):113144. doi: 10.1016/j.celrep.2023.113144. Epub 2023 Sep 19. Cell Rep. 2023. PMID: 37729060 Free PMC article.
Inaugurating High-Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection.
Jo A, Green A, Medina JE, Iyer S, Ohman AW, McCarthy ET, Reinhardt F, Gerton T, Demehin D, Mishra R, Kolin DL, Zheng H, Cheon J, Crum CP, Weinberg RA, Rueda BR, Castro CM, Dinulescu DM, Lee H. Jo A, et al. Among authors: weinberg ra. Adv Sci (Weinh). 2023 Sep;10(27):e2301930. doi: 10.1002/advs.202301930. Epub 2023 Jul 23. Adv Sci (Weinh). 2023. PMID: 37485618 Free PMC article.
Ether lipids influence cancer cell fate by modulating iron uptake.
Henry WS, Müller S, Yang JS, Innes-Gold S, Das S, Reinhardt F, Sigmund K, Phadnis VV, Wan Z, Eaton E, Sampaio JL, Bell GW, Viravalli A, Hammond PT, Kamm RD, Cohen AE, Boehnke N, Hsu VW, Levental KR, Rodriguez R, Weinberg RA. Henry WS, et al. Among authors: weinberg ra. bioRxiv [Preprint]. 2024 Mar 21:2024.03.20.585922. doi: 10.1101/2024.03.20.585922. bioRxiv. 2024. PMID: 38562716 Free PMC article. Preprint.
Profiling extracellular vesicles in circulation enables the early detection of ovarian cancer.
Jo A, Green A, Medina JE, Iyer S, Ohman AW, McCarthy ET, Reinhardt F, Gerton T, Demehin D, Mishra R, Kolin DL, Zheng H, Crum CP, Weinberg RA, Rueda BR, Castro CM, Dinulescu DM, Lee H. Jo A, et al. Among authors: weinberg ra. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524549. doi: 10.1101/2023.01.19.524549. bioRxiv. 2023. PMID: 36711872 Free PMC article. Preprint.
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells.
Lambert AW, Fiore C, Chutake Y, Verhaar ER, Strasser PC, Chen MW, Farouq D, Das S, Li X, Eaton EN, Zhang Y, Liu Donaher J, Engstrom I, Reinhardt F, Yuan B, Gupta S, Wollison B, Eaton M, Bierie B, Carulli J, Olson ER, Guenther MG, Weinberg RA. Lambert AW, et al. Among authors: weinberg ra. Dev Cell. 2022 Dec 19;57(24):2714-2730.e8. doi: 10.1016/j.devcel.2022.11.015. Dev Cell. 2022. PMID: 36538894 Free PMC article.
Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis.
Zhang Y, Donaher JL, Das S, Li X, Reinhardt F, Krall JA, Lambert AW, Thiru P, Keys HR, Khan M, Hofree M, Wilson MM, Yedier-Bayram O, Lack NA, Onder TT, Bagci-Onder T, Tyler M, Tirosh I, Regev A, Lees JA, Weinberg RA. Zhang Y, et al. Among authors: weinberg ra. Nat Cell Biol. 2022 Apr;24(4):554-564. doi: 10.1038/s41556-022-00877-0. Epub 2022 Apr 11. Nat Cell Biol. 2022. PMID: 35411083 Free PMC article.
448 results