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Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.
Liang J, Nagahashi M, Kim EY, Harikumar KB, Yamada A, Huang WC, Hait NC, Allegood JC, Price MM, Avni D, Takabe K, Kordula T, Milstien S, Spiegel S. Liang J, et al. Among authors: takabe k. Cancer Cell. 2013 Jan 14;23(1):107-20. doi: 10.1016/j.ccr.2012.11.013. Epub 2012 Dec 27. Cancer Cell. 2013. PMID: 23273921 Free PMC article.
High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival.
Yamada A, Ishikawa T, Ota I, Kimura M, Shimizu D, Tanabe M, Chishima T, Sasaki T, Ichikawa Y, Morita S, Yoshiura K, Takabe K, Endo I. Yamada A, et al. Among authors: takabe k. Breast Cancer Res Treat. 2013 Feb;137(3):773-82. doi: 10.1007/s10549-012-2398-5. Epub 2013 Jan 4. Breast Cancer Res Treat. 2013. PMID: 23288347 Free PMC article.
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer.
Nagahashi M, Hait NC, Maceyka M, Avni D, Takabe K, Milstien S, Spiegel S. Nagahashi M, et al. Among authors: takabe k. Adv Biol Regul. 2014 Jan;54:112-20. doi: 10.1016/j.jbior.2013.10.001. Epub 2013 Oct 16. Adv Biol Regul. 2014. PMID: 24210073 Free PMC article. Review.
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.
Harikumar KB, Yester JW, Surace MJ, Oyeniran C, Price MM, Huang WC, Hait NC, Allegood JC, Yamada A, Kong X, Lazear HM, Bhardwaj R, Takabe K, Diamond MS, Luo C, Milstien S, Spiegel S, Kordula T. Harikumar KB, et al. Among authors: takabe k. Nat Immunol. 2014 Mar;15(3):231-8. doi: 10.1038/ni.2810. Epub 2014 Jan 26. Nat Immunol. 2014. PMID: 24464131 Free PMC article.
452 results