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Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis.
Baltanás FC, Mucientes-Valdivieso C, Lorenzo-Martín LF, Fernández-Parejo N, García-Navas R, Segrelles C, Calzada N, Fuentes-Mateos R, Paramio JM, Bustelo XR, Santos E. Baltanás FC, et al. Cancers (Basel). 2021 Apr 29;13(9):2152. doi: 10.3390/cancers13092152. Cancers (Basel). 2021. PMID: 33946974 Free PMC article.
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.
Fernández-Pisonero I, Clavaín L, Robles-Valero J, Lorenzo-Martín LF, Caloto R, Nieto B, García-Macías C, Oeste CL, Sánchez-Martín M, Abad A, Hortal A, Caballero D, González M, Dosil M, Alarcón B, Bustelo XR. Fernández-Pisonero I, et al. Among authors: lorenzo martin lf. Cell Rep. 2022 Mar 15;38(11):110522. doi: 10.1016/j.celrep.2022.110522. Cell Rep. 2022. PMID: 35294890 Free article.
Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors.
Clavaín L, Fernández-Pisonero I, Movilla N, Lorenzo-Martín LF, Nieto B, Abad A, García-Navas R, Llorente-González C, Sánchez-Martín M, Vicente-Manzanares M, Santos E, Alarcón B, García-Aznar JM, Dosil M, Bustelo XR. Clavaín L, et al. Among authors: lorenzo martin lf. Oncogene. 2023 Jan;42(5):389-405. doi: 10.1038/s41388-022-02563-9. Epub 2022 Dec 7. Oncogene. 2023. PMID: 36476833 Free PMC article.
Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo.
Lorenzo-Martín LF, Hübscher T, Bowler AD, Broguiere N, Langer J, Tillard L, Nikolaev M, Radtke F, Lutolf MP. Lorenzo-Martín LF, et al. Nature. 2024 May;629(8011):450-457. doi: 10.1038/s41586-024-07330-2. Epub 2024 Apr 24. Nature. 2024. PMID: 38658753 Free PMC article.
Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions.
Lorenzo-Martín LF, Menacho-Márquez M, Fabbiano S, Al-Massadi O, Abad A, Rodríguez-Fdez S, Sevilla MA, Montero MJ, Diéguez C, Nogueiras R, Bustelo XR. Lorenzo-Martín LF, et al. J Endocrinol. 2019 Mar 1;240(3):483-496. doi: 10.1530/JOE-18-0623. J Endocrinol. 2019. PMID: 30703063 Free PMC article.
31 results