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α1A-Adrenergic Receptor Antagonism Improves Erectile and Cavernosal Responses in Rats With Cavernous Nerve Injury and Enhances Neurogenic Responses in Human Corpus Cavernosum From Patients With Erectile Dysfunction Secondary to Radical Prostatectomy.
Martínez-Salamanca JI, La Fuente JM, Martínez-Salamanca E, Fernández A, Pepe-Cardoso AJ, Louro N, Carballido J, Angulo J. Martínez-Salamanca JI, et al. Among authors: angulo j. J Sex Med. 2016 Dec;13(12):1844-1857. doi: 10.1016/j.jsxm.2016.10.005. Epub 2016 Nov 15. J Sex Med. 2016. PMID: 27864032
L-cysteine/hydrogen sulfide pathway induces cGMP-dependent relaxation of corpus cavernosum and penile arteries from patients with erectile dysfunction and improves arterial vasodilation induced by PDE5 inhibition.
La Fuente JM, Fernández A, Pepe-Cardoso AJ, Martínez-Salamanca JI, Louro N, Angulo J. La Fuente JM, et al. Among authors: angulo j. Eur J Pharmacol. 2019 Nov 15;863:172675. doi: 10.1016/j.ejphar.2019.172675. Epub 2019 Sep 19. Eur J Pharmacol. 2019. PMID: 31542487
Erectile dysfunction is associated with defective L-cysteine/hydrogen sulfide pathway in human corpus cavernosum and penile arteries.
La Fuente JM, Sevilleja-Ortiz A, García-Rojo E, El Assar M, Fernández A, Pepe-Cardoso AJ, Martínez-Salamanca JI, Romero-Otero J, Rodríguez-Mañas L, Angulo J. La Fuente JM, et al. Among authors: angulo j. Eur J Pharmacol. 2020 Oct 5;884:173370. doi: 10.1016/j.ejphar.2020.173370. Epub 2020 Jul 23. Eur J Pharmacol. 2020. PMID: 32712093
Ageing-induced hypercontractility is related to functional enhancement of STIM/Orai and upregulation of Orai 3 in rat and human penile tissue.
Sevilleja-Ortiz A, El Assar M, García-Rojo E, García-Gómez B, Fernández A, Sánchez-Ferrer A, La Fuente JM, Romero-Otero J, Rodríguez-Mañas L, Angulo J. Sevilleja-Ortiz A, et al. Among authors: angulo j. Mech Ageing Dev. 2021 Dec;200:111590. doi: 10.1016/j.mad.2021.111590. Epub 2021 Oct 23. Mech Ageing Dev. 2021. PMID: 34699858
Early manifestation of aging-related vascular dysfunction in human penile vasculature-A potential explanation for the role of erectile dysfunction as a harbinger of systemic vascular disease.
Assar ME, Angulo J, García-Rojo E, Sevilleja-Ortiz A, García-Gómez B, Fernández A, Sánchez-Ferrer A, La Fuente JM, Romero-Otero J, Rodríguez-Mañas L. Assar ME, et al. Among authors: angulo j. Geroscience. 2022 Feb;44(1):485-501. doi: 10.1007/s11357-021-00507-x. Epub 2021 Dec 28. Geroscience. 2022. PMID: 34962617 Free PMC article.
889 results