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Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy.
Le K, Soth MJ, Cross JB, Liu G, Ray WJ, Ma J, Goodwani SG, Acton PJ, Buggia-Prevot V, Akkermans O, Barker J, Conner ML, Jiang Y, Liu Z, McEwan P, Warner-Schmidt J, Xu A, Zebisch M, Heijnen CJ, Abrahams B, Jones P. Le K, et al. Among authors: abrahams b. J Med Chem. 2023 Jul 27;66(14):9954-9971. doi: 10.1021/acs.jmedchem.3c00788. Epub 2023 Jul 12. J Med Chem. 2023. PMID: 37436942
Complexes of 2,4,6-trihydroxybenzoic acid: effects of intramolecular hydrogen bonding on ligand geometry and metal binding modes.
Abrahams BF, Commons CJ, Hudson TA, Sanchez Arlt R, Ahl R, Carajias ED, Chan JWK, Guo Z, Hill RE, McGinty A, Peters NL, Poon JYP, Qu J, Qu J, Rochette EE, Walkear C, Wang H, Wu H, Xu C, Zhang J. Abrahams BF, et al. Acta Crystallogr C Struct Chem. 2022 Nov 1;78(Pt 11):653-670. doi: 10.1107/S2053229622009901. Epub 2022 Oct 25. Acta Crystallogr C Struct Chem. 2022. PMID: 36331890 Free PMC article.
144 results