Borghoff S - Search Results

1

Optimizing androgen receptor prioritization using high-throughput assay-based activity models.

Bever RJ, Edwards SW, Antonijevic T, Nelms MD, Ring C, Harris D, Lynn SG, Williams D, Chappell G, Boyles R, Borghoff S, Markey KJ. Bever RJ, et al. Among authors: borghoff s. Front Toxicol. 2024 Mar 11;6:1347364. doi: 10.3389/ftox.2024.1347364. eCollection 2024. Front Toxicol. 2024. PMID: 38529103 Free PMC article.

2

Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to α2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.

Borghoff SJ, Ring C, Banton MI, Leavens TL. Borghoff SJ, et al. J Appl Toxicol. 2017 May;37(5):621-640. doi: 10.1002/jat.3412. Epub 2016 Nov 24. J Appl Toxicol. 2017. PMID: 27885692 Free PMC article.

3

An Adverse Outcome Pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events.

Proctor DM, Suh M, Chappell G, Borghoff SJ, Thompson CM, Wiench K, Finch L, Ellis-Hutchings R. Proctor DM, et al. Regul Toxicol Pharmacol. 2018 Jul;96:30-40. doi: 10.1016/j.yrtph.2018.04.016. Epub 2018 Apr 21. Regul Toxicol Pharmacol. 2018. PMID: 29684431 Free article. Review.

4

A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates.

Suh M, Proctor D, Chappell G, Rager J, Thompson C, Borghoff S, Finch L, Ellis-Hutchings R, Wiench K. Suh M, et al. Among authors: borghoff s. Toxicology. 2018 Jun 1;402-403:50-67. doi: 10.1016/j.tox.2018.04.006. Epub 2018 Apr 22. Toxicology. 2018. PMID: 29689363 Free article. Review.

5

Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans.

Thompson CM, Suh M, Proctor DM, Chappell G, Borghoff S, Ellis-Hutchings R, Wiench K, Finch L. Thompson CM, et al. Among authors: borghoff s. Regul Toxicol Pharmacol. 2018 Jul;96:178-189. doi: 10.1016/j.yrtph.2018.05.006. Epub 2018 May 5. Regul Toxicol Pharmacol. 2018. PMID: 29738809 Free article. Review.

6

Identifying Attributes That Influence In Vitro-to-In Vivo Concordance by Comparing In Vitro Tox21 Bioactivity Versus In Vivo DrugMatrix Transcriptomic Responses Across 130 Chemicals.

Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh JH, Auerbach SS, Rager JE. Klaren WD, et al. Among authors: borghoff s. Toxicol Sci. 2019 Jan 1;167(1):157-171. doi: 10.1093/toxsci/kfy220. Toxicol Sci. 2019. PMID: 30202884 Free PMC article.

7

A Framework for Systematic Evaluation and Quantitative Integration of Mechanistic Data in Assessments of Potential Human Carcinogens.

Wikoff DS, Rager JE, Chappell GA, Fitch S, Haws L, Borghoff SJ. Wikoff DS, et al. Among authors: borghoff sj. Toxicol Sci. 2019 Feb 1;167(2):322-335. doi: 10.1093/toxsci/kfy279. Toxicol Sci. 2019. PMID: 30423162

8

Lack of potential carcinogenicity for aspartame - Systematic evaluation and integration of mechanistic data into the totality of the evidence.

Wikoff DS, Chappell GA, Fitch S, Doepker CL, Borghoff SJ. Wikoff DS, et al. Among authors: borghoff sj. Food Chem Toxicol. 2020 Jan;135:110866. doi: 10.1016/j.fct.2019.110866. Epub 2019 Oct 12. Food Chem Toxicol. 2020. PMID: 31614175 Free article.

9

Lack of potential carcinogenicity for sucralose - Systematic evaluation and integration of mechanistic data into the totality of the evidence.

Chappell GA, Borghoff SJ, Pham LL, Doepker CL, Wikoff DS. Chappell GA, et al. Among authors: borghoff sj. Food Chem Toxicol. 2020 Jan;135:110898. doi: 10.1016/j.fct.2019.110898. Epub 2019 Oct 22. Food Chem Toxicol. 2020. PMID: 31654706 Free article.

10

Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes.

Chappell GA, Britt JK, Borghoff SJ. Chappell GA, et al. Among authors: borghoff sj. Food Chem Toxicol. 2020 Jun;140:111310. doi: 10.1016/j.fct.2020.111310. Epub 2020 Apr 7. Food Chem Toxicol. 2020. PMID: 32275932 Free article.

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