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Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion.
Malarikova D, Jorda R, Kupcova K, Senavova J, Dolnikova A, Pokorna E, Kazantsev D, Nozickova K, Sovilj D, Bellanger C, Chiron D, Andera L, Krystof V, Strnad M, Helman K, Klanova M, Trneny M, Havranek O, Klener P. Malarikova D, et al. Among authors: andera l. Exp Hematol Oncol. 2024 Mar 25;13(1):34. doi: 10.1186/s40164-024-00499-2. Exp Hematol Oncol. 2024. PMID: 38528594 Free PMC article.
Blockage of BCL-XL overcomes venetoclax resistance across BCL2-positive lymphoid malignancies irrespective of BIM status.
Dolnikova A, Kazantsev D, Klanova M, Pokorna E, Sovilj D, Kelemen CD, Tuskova L, Hoferkova E, Mraz M, Helman K, Curik N, Machova Polakova K, Anděra L, Trněný M, Klener P. Dolnikova A, et al. Among authors: andera l. Blood Adv. 2024 May 7:bloodadvances.2024012906. doi: 10.1182/bloodadvances.2024012906. Online ahead of print. Blood Adv. 2024. PMID: 38713893
Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.
Stemberkova-Hubackova S, Zobalova R, Dubisova M, Smigova J, Dvorakova S, Korinkova K, Ezrova Z, Endaya B, Blazkova K, Vlcak E, Brisudova P, Le DT, Juhas S, Rosel D, Daniela Kelemen C, Sovilj D, Vacurova E, Cajka T, Filimonenko V, Dong L, Andera L, Hozak P, Brabek J, Bielcikova Z, Stursa J, Werner L, Neuzil J. Stemberkova-Hubackova S, et al. Among authors: andera l. Clin Transl Med. 2022 Mar;12(3):e645. doi: 10.1002/ctm2.645. Clin Transl Med. 2022. PMID: 35352502 Free PMC article. No abstract available.
Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
Klanova M, Kazantsev D, Pokorna E, Zikmund T, Karolova J, Behounek M, Renesova N, Sovilj D, Kelemen CD, Helman K, Jaksa R, Havranek O, Andera L, Trneny M, Klener P. Klanova M, et al. Among authors: andera l. Mol Cancer Ther. 2022 Jan;21(1):89-99. doi: 10.1158/1535-7163.MCT-21-0511. Epub 2021 Nov 2. Mol Cancer Ther. 2022. PMID: 34728569 Free PMC article.
BH3 Mimetics in Hematologic Malignancies.
Klener P, Sovilj D, Renesova N, Andera L. Klener P, et al. Among authors: andera l. Int J Mol Sci. 2021 Sep 21;22(18):10157. doi: 10.3390/ijms221810157. Int J Mol Sci. 2021. PMID: 34576319 Free PMC article. Review.
80 results