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Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines.
Eltayeb K, Alfieri R, Fumarola C, Bonelli M, Galetti M, Cavazzoni A, Digiacomo G, Galvani F, Vacondio F, Lodola A, Mor M, Minari R, Tiseo M, La Monica S, Giorgio Petronini P. Eltayeb K, et al. Among authors: bonelli m. Biochem Pharmacol. 2024 Mar 24:116161. doi: 10.1016/j.bcp.2024.116161. Online ahead of print. Biochem Pharmacol. 2024. PMID: 38522556 Free article.
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines.
La Monica S, Galetti M, Alfieri RR, Cavazzoni A, Ardizzoni A, Tiseo M, Capelletti M, Goldoni M, Tagliaferri S, Mutti A, Fumarola C, Bonelli M, Generali D, Petronini PG. La Monica S, et al. Among authors: bonelli m. Biochem Pharmacol. 2009 Sep 1;78(5):460-8. doi: 10.1016/j.bcp.2009.04.033. Epub 2009 May 7. Biochem Pharmacol. 2009. PMID: 19427302
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines.
Galetti M, Alfieri RR, Cavazzoni A, La Monica S, Bonelli M, Fumarola C, Mozzoni P, De Palma G, Andreoli R, Mutti A, Mor M, Tiseo M, Ardizzoni A, Petronini PG. Galetti M, et al. Among authors: bonelli m. Biochem Pharmacol. 2010 Jul 15;80(2):179-87. doi: 10.1016/j.bcp.2010.03.033. Epub 2010 Apr 2. Biochem Pharmacol. 2010. PMID: 20363215
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models.
La Monica S, Vacondio F, Eltayeb K, Lodola A, Volta F, Viglioli M, Ferlenghi F, Galvani F, Galetti M, Bonelli M, Fumarola C, Cavazzoni A, Flammini L, Verzè M, Minari R, Petronini PG, Tiseo M, Mor M, Alfieri R. La Monica S, et al. Among authors: bonelli m. Sci Rep. 2024 Mar 18;14(1):6491. doi: 10.1038/s41598-024-57028-8. Sci Rep. 2024. PMID: 38499619 Free PMC article.
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines.
Alfieri RR, Galetti M, Tramonti S, Andreoli R, Mozzoni P, Cavazzoni A, Bonelli M, Fumarola C, La Monica S, Galvani E, De Palma G, Mutti A, Mor M, Tiseo M, Mari E, Ardizzoni A, Petronini PG. Alfieri RR, et al. Among authors: bonelli m. Mol Cancer. 2011 Nov 23;10:143. doi: 10.1186/1476-4598-10-143. Mol Cancer. 2011. PMID: 22111840 Free PMC article.
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer.
Galvani E, Alfieri R, Giovannetti E, Cavazzoni A, La Monica S, Galetti M, Fumarola C, Bonelli M, Mor M, Tiseo M, Peters GJ, Petronini PG, Ardizzoni A. Galvani E, et al. Among authors: bonelli m. Curr Pharm Des. 2013;19(5):818-32. Curr Pharm Des. 2013. PMID: 22973953 Review.
273 results