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Spatial omics techniques and data analysis for cancer immunotherapy applications.
Zhang Y, Lee RY, Tan CW, Guo X, Yim WW, Lim JC, Wee FY, Yang WU, Kharbanda M, Lee JJ, Ngo NT, Leow WQ, Loo LH, Lim TK, Sobota RM, Lau MC, Davis MJ, Yeong J. Zhang Y, et al. Among authors: sobota rm. Curr Opin Biotechnol. 2024 Mar 22;87:103111. doi: 10.1016/j.copbio.2024.103111. Online ahead of print. Curr Opin Biotechnol. 2024. PMID: 38520821 Review.
Unveiling the Influence of Tumor Microenvironment and Spatial Heterogeneity on Temozolomide Resistance in Glioblastoma Using an Advanced Human In Vitro Model of the Blood-Brain Barrier and Glioblastoma.
Lam MS, Aw JJ, Tan D, Vijayakumar R, Lim HYG, Yada S, Pang QY, Barker N, Tang C, Ang BT, Sobota RM, Pavesi A. Lam MS, et al. Among authors: sobota rm. Small. 2023 Dec;19(52):e2302280. doi: 10.1002/smll.202302280. Epub 2023 Aug 30. Small. 2023. PMID: 37649234
PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin.
Feng J, Chuah YH, Liang Y, Cipta NO, Zeng Y, Warrier T, Elfar GARE, Yoon J, Grinchuk OV, Tay EXY, Lok KZ, Zheng ZQ, Khong ZJ, Chong ZS, Teo J, Sanford EM, Neo CJY, Chiu HY, Leung JY, Wang LC, Lim YT, Zhao T, Sobota RM, Crasta KC, Tergaonkar V, Taneja R, Ng SY, Cheok CF, Ling SC, Loh YH, Ong DST. Feng J, et al. Among authors: sobota rm. Nucleic Acids Res. 2024 May 29:gkae457. doi: 10.1093/nar/gkae457. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38808662
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development.
Wirjanata G, Lin J, Dziekan JM, El Sahili A, Chung Z, Tjia S, Binte Zulkifli NE, Boentoro J, Tham R, Jia LS, Go KD, Yu H, Partridge A, Olsen D, Prabhu N, Sobota RM, Nordlund P, Lescar J, Bozdech Z. Wirjanata G, et al. Among authors: sobota rm. Cell Chem Biol. 2024 Apr 18;31(4):743-759.e8. doi: 10.1016/j.chembiol.2024.03.002. Epub 2024 Apr 8. Cell Chem Biol. 2024. PMID: 38593807
74 results