Hamada K - Search Results

1

Structure of the human Bre1 complex bound to the nucleosome.

Onishi S, Uchiyama K, Sato K, Okada C, Kobayashi S, Hamada K, Nishizawa T, Nureki O, Ogata K, Sengoku T. Onishi S, et al. Among authors: hamada k. Nat Commun. 2024 Mar 22;15(1):2580. doi: 10.1038/s41467-024-46910-8. Nat Commun. 2024. PMID: 38519511 Free PMC article.

2

Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.

Sato K, Kumar A, Hamada K, Okada C, Oguni A, Machiyama A, Sakuraba S, Nishizawa T, Nureki O, Kono H, Ogata K, Sengoku T. Sato K, et al. Among authors: hamada k. Nat Commun. 2021 Nov 15;12(1):6605. doi: 10.1038/s41467-021-26913-5. Nat Commun. 2021. PMID: 34782608 Free PMC article.

3

Crystallization of the Ets1-Runx1-CBFβ-DNA complex formed on the TCRα gene enhancer.

Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Baba S, Sato K, Ogata K. Shiina M, et al. Among authors: hamada k. Acta Crystallogr F Struct Biol Commun. 2014 Oct;70(Pt 10):1380-4. doi: 10.1107/S2053230X14018470. Epub 2014 Sep 25. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 25286944 Free PMC article.

4

Structural basis of transcription regulation by CNC family transcription factor, Nrf2.

Sengoku T, Shiina M, Suzuki K, Hamada K, Sato K, Uchiyama A, Kobayashi S, Oguni A, Itaya H, Kasahara K, Moriwaki H, Watanabe C, Honma T, Okada C, Baba S, Ohta T, Motohashi H, Yamamoto M, Ogata K. Sengoku T, et al. Among authors: hamada k. Nucleic Acids Res. 2022 Nov 28;50(21):12543-12557. doi: 10.1093/nar/gkac1102. Nucleic Acids Res. 2022. PMID: 36454022 Free PMC article.

5

A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides.

Vinogradov AA, Zhang Y, Hamada K, Kobayashi S, Ogata K, Sengoku T, Goto Y, Suga H. Vinogradov AA, et al. Among authors: hamada k. J Am Chem Soc. 2024 Mar 27;146(12):8058-8070. doi: 10.1021/jacs.3c12037. Epub 2024 Mar 16. J Am Chem Soc. 2024. PMID: 38491946

6

De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors.

Vinogradov AA, Zhang Y, Hamada K, Chang JS, Okada C, Nishimura H, Terasaka N, Goto Y, Ogata K, Sengoku T, Onaka H, Suga H. Vinogradov AA, et al. Among authors: hamada k. J Am Chem Soc. 2022 Nov 9;144(44):20332-20341. doi: 10.1021/jacs.2c07937. Epub 2022 Oct 25. J Am Chem Soc. 2022. PMID: 36282922 Free PMC article.

7

A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.

Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Uchiyama A, Baba S, Sato K, Yamamoto M, Ogata K. Shiina M, et al. Among authors: hamada k. J Mol Biol. 2015 Apr 24;427(8):1655-69. doi: 10.1016/j.jmb.2014.07.020. Epub 2014 Jul 30. J Mol Biol. 2015. PMID: 25083921 Free article.

8

The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b.

Yamashita K, Suzuki A, Satoh Y, Ide M, Amano Y, Masuda-Hirata M, Hayashi YK, Hamada K, Ogata K, Ohno S. Yamashita K, et al. Among authors: hamada k. Biochem Biophys Res Commun. 2010 Jan 1;391(1):812-7. doi: 10.1016/j.bbrc.2009.11.144. Epub 2009 Nov 27. Biochem Biophys Res Commun. 2010. PMID: 19945424

9

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy.

Saitsu H, Kato M, Mizuguchi T, Hamada K, Osaka H, Tohyama J, Uruno K, Kumada S, Nishiyama K, Nishimura A, Okada I, Yoshimura Y, Hirai S, Kumada T, Hayasaka K, Fukuda A, Ogata K, Matsumoto N. Saitsu H, et al. Among authors: hamada k. Nat Genet. 2008 Jun;40(6):782-8. doi: 10.1038/ng.150. Epub 2008 May 11. Nat Genet. 2008. PMID: 18469812

10

Rational approach to the synthesis, evaluation, and (68)ga labeling of a novel 4-anilinoquinoline epidermal growth factor receptor inhibitor as a new imaging agent that selectively targets the epidermal growth factor receptor tyrosine kinase.

Theeraladanon C, Takahashi N, Shiina M, Hamada K, Takada Y, Endo H, Tateishi U, Oka T, Ogata K, Inoue T. Theeraladanon C, et al. Among authors: hamada k. Cancer Biother Radiopharm. 2010 Aug;25(4):479-85. doi: 10.1089/cbr.2009.0614. Cancer Biother Radiopharm. 2010. PMID: 20735208

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