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Einbau von (Bioaktiven) Äquatorialen Liganden in Platin(IV)-Komplexe.
Kastner A, Schueffl H, Yassemipour PA, Keppler BK, Heffeter P, Kowol CR. Kastner A, et al. Among authors: schueffl h. Angew Chem Weinheim Bergstr Ger. 2023 Nov 13;135(46):e202311468. doi: 10.1002/ange.202311468. Epub 2023 Oct 13. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38516539 Free PMC article.
Insertion of (Bioactive) Equatorial Ligands into Platinum(IV) Complexes.
Kastner A, Schueffl H, Yassemipour PA, Keppler BK, Heffeter P, Kowol CR. Kastner A, et al. Among authors: schueffl h. Angew Chem Int Ed Engl. 2023 Nov 13;62(46):e202311468. doi: 10.1002/anie.202311468. Epub 2023 Oct 13. Angew Chem Int Ed Engl. 2023. PMID: 37703130 Free PMC article.
A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo.
Caban M, Koblmueller B, Groza D, Schueffl HH, Terenzi A, Tolios A, Mohr T, Mathuber M, Kryeziu K, Jaunecker C, Pirker C, Keppler BK, Berger W, Kowol CR, Heffeter P. Caban M, et al. Among authors: schueffl hh. Cancer Lett. 2023 Jul 1;565:216237. doi: 10.1016/j.canlet.2023.216237. Epub 2023 May 19. Cancer Lett. 2023. PMID: 37211067 Free article.
The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation.
Gushchina V, Kupper N, Schwarzkopf M, Frisch G, Piatek K, Aigner C, Michel A, Schueffl H, Iamartino L, Elajnaf T, Manhardt T, Vlasaty A, Heffeter P, Bassetto M, Kállay E, Schepelmann M. Gushchina V, et al. Among authors: schueffl h. Front Pharmacol. 2023 Apr 20;14:1151144. doi: 10.3389/fphar.2023.1151144. eCollection 2023. Front Pharmacol. 2023. PMID: 37153788 Free PMC article.
CD47-targeted cancer immunogene therapy: Secreted SIRPα-Fc fusion protein eradicates tumors by macrophage and NK cell activation.
Billerhart M, Schönhofer M, Schueffl H, Polzer W, Pichler J, Decker S, Taschauer A, Maier J, Anton M, Eckmann S, Blaschek M, Heffeter P, Sami H, Ogris M. Billerhart M, et al. Among authors: schueffl h. Mol Ther Oncolytics. 2021 Oct 1;23:192-204. doi: 10.1016/j.omto.2021.09.005. eCollection 2021 Dec 17. Mol Ther Oncolytics. 2021. PMID: 34729396 Free PMC article.
Albumin-targeting of an oxaliplatin-releasing platinum(iv) prodrug results in pronounced anticancer activity due to endocytotic drug uptake in vivo.
Schueffl H, Theiner S, Hermann G, Mayr J, Fronik P, Groza D, van Schonhooven S, Galvez L, Sommerfeld NS, Schintlmeister A, Reipert S, Wagner M, Mader RM, Koellensperger G, Keppler BK, Berger W, Kowol CR, Legin A, Heffeter P. Schueffl H, et al. Chem Sci. 2021 Aug 26;12(38):12587-12599. doi: 10.1039/d1sc03311e. eCollection 2021 Oct 6. Chem Sci. 2021. PMID: 34703544 Free PMC article.
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