Aigbirhio F - Search Results

1

Detection of Small-Molecule Interactions with Fibrillar Tau Protein Aggregates Using Microscale Thermophoresis.

Zhao Y, Mikes A, Tóth G, Aigbirhio F. Zhao Y, et al. Among authors: aigbirhio f. Methods Mol Biol. 2024;2754:205-217. doi: 10.1007/978-1-0716-3629-9_12. Methods Mol Biol. 2024. PMID: 38512669

2

Probing small molecule binding to amyloid fibrils.

Buell AK, Esbjörner EK, Riss PJ, White DA, Aigbirhio FI, Toth G, Welland ME, Dobson CM, Knowles TP. Buell AK, et al. Phys Chem Chem Phys. 2011 Dec 7;13(45):20044-52. doi: 10.1039/c1cp22283j. Epub 2011 Oct 17. Phys Chem Chem Phys. 2011. PMID: 22006124 Review.

3

Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis.

Fisher E, Zhao Y, Richardson R, Janik M, Buell AK, Aigbirhio FI, Tóth G. Fisher E, et al. ACS Chem Neurosci. 2017 Sep 20;8(9):2088-2095. doi: 10.1021/acschemneuro.7b00228. Epub 2017 Jul 6. ACS Chem Neurosci. 2017. PMID: 28640595

4

Systemic α-synuclein injection triggers selective neuronal pathology as seen in patients with Parkinson's disease.

Kuan WL, Stott K, He X, Wood TC, Yang S, Kwok JCF, Hall K, Zhao Y, Tietz O, Aigbirhio FI, Vernon AC, Barker RA. Kuan WL, et al. Among authors: aigbirhio fi. Mol Psychiatry. 2021 Feb;26(2):556-567. doi: 10.1038/s41380-019-0608-9. Epub 2019 Nov 22. Mol Psychiatry. 2021. PMID: 31758091 Free PMC article.

5

Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models.

McMurray L, Macdonald JA, Ramakrishnan NK, Zhao Y, Williamson DW, Tietz O, Zhou X, Kealey S, Fagan SG, Smolek T, Cubinkova V, Žilka N, Spillantini MG, Tolkovsky AM, Goedert M, Aigbirhio FI. McMurray L, et al. ACS Chem Neurosci. 2021 Jun 2;12(11):1885-1893. doi: 10.1021/acschemneuro.0c00790. Epub 2021 Mar 10. ACS Chem Neurosci. 2021. PMID: 33689290 Free PMC article.

6

A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein.

Zhao Y, Tietz O, Kuan WL, Haji-Dheere AK, Thompson S, Vallin B, Ronchi E, Tóth G, Klenerman D, Aigbirhio FI. Zhao Y, et al. Chem Sci. 2020 Apr 21;11(18):4773-4778. doi: 10.1039/c9sc05620c. Chem Sci. 2020. PMID: 34122933 Free PMC article.

7

Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease.

Emin D, Zhang YP, Lobanova E, Miller A, Li X, Xia Z, Dakin H, Sideris DI, Lam JYL, Ranasinghe RT, Kouli A, Zhao Y, De S, Knowles TPJ, Vendruscolo M, Ruggeri FS, Aigbirhio FI, Williams-Gray CH, Klenerman D. Emin D, et al. Nat Commun. 2022 Sep 20;13(1):5512. doi: 10.1038/s41467-022-33252-6. Nat Commun. 2022. PMID: 36127374 Free PMC article.

8

Mapping the binding site topology of amyloid protein aggregates using multivalent ligands.

Sanna E, Rodrigues M, Fagan SG, Chisholm TS, Kulenkampff K, Klenerman D, Spillantini MG, Aigbirhio FI, Hunter CA. Sanna E, et al. Chem Sci. 2021 Jun 7;12(25):8892-8899. doi: 10.1039/d1sc01263k. eCollection 2021 Jul 1. Chem Sci. 2021. PMID: 34257890 Free PMC article.

9

PET Ligands for Imaging Mutant Huntingtin Aggregates: A Case Study in Non-For-Profit Scientific Management.

Dickmann CGF, Milicevic Sephton S, Barker RA, Aigbirhio FI. Dickmann CGF, et al. Among authors: aigbirhio fi. Chembiochem. 2024 May 2:e202400152. doi: 10.1002/cbic.202400152. Online ahead of print. Chembiochem. 2024. PMID: 38695673 Review.

10

In vivo tau PET imaging in dementia: Pathophysiology, radiotracer quantification, and a systematic review of clinical findings.

Hall B, Mak E, Cervenka S, Aigbirhio FI, Rowe JB, O'Brien JT. Hall B, et al. Ageing Res Rev. 2017 Jul;36:50-63. doi: 10.1016/j.arr.2017.03.002. Epub 2017 Mar 15. Ageing Res Rev. 2017. PMID: 28315409 Review.

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