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Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex.
Huuki-Myers L, Spangler A, Eagles N, Montgomery KD, Kwon SH, Guo B, Grant-Peters M, Divecha HR, Tippani M, Sriworarat C, Nguyen AB, Ravichandran P, Tran MN, Seyedian A; PsychENCODE consortium; Hyde TM, Kleinman JE, Battle A, Page SC, Ryten M, Hicks SC, Martinowich K, Collado-Torres L, Maynard KR. Huuki-Myers L, et al. Among authors: kleinman je. bioRxiv [Preprint]. 2023 Feb 15:2023.02.15.528722. doi: 10.1101/2023.02.15.528722. bioRxiv. 2023. PMID: 36824961 Free PMC article. Preprint.
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.
Carnes MU, Quach BC, Zhou L, Han S, Tao R, Mandal M, Deep-Soboslay A, Marks JA, Page GP, Maher BS, Jaffe AE, Won H, Bierut LJ, Hyde TM, Kleinman JE, Johnson EO, Hancock DB. Carnes MU, et al. Among authors: kleinman je. medRxiv [Preprint]. 2023 Sep 18:2023.09.18.23295431. doi: 10.1101/2023.09.18.23295431. medRxiv. 2023. PMID: 37790540 Free PMC article. Preprint.
Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.
Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Matoba N, Jiao C, Kim M, Tsai E, Hoh C, Aygün N, Walker RL, Chatzinakos C, Clarke D, Pratt H, Consortium P, Peters MA, Gerstein M, Daskalakis NP, Weng Z, Jaffe AE, Kleinman JE, Hyde TM, Weinberger DR, Bray NJ, Sestan N, Geschwind DH, Roeder K, Gusev A, Pasaniuc B, Stein JL, Love MI, Pollard KS, Liu C, Gandal MJ. Wen C, et al. Among authors: kleinman je. medRxiv [Preprint]. 2023 Mar 6:2023.03.03.23286706. doi: 10.1101/2023.03.03.23286706. medRxiv. 2023. PMID: 36945630 Free PMC article. Preprint.
Investigating the neuroimmunogenic architecture of schizophrenia.
Birnbaum R, Jaffe AE, Chen Q, Shin JH; BrainSeq Consortium; Kleinman JE, Hyde TM, Weinberger DR. Birnbaum R, et al. Among authors: kleinman je. Mol Psychiatry. 2018 May;23(5):1251-1260. doi: 10.1038/mp.2017.89. Epub 2017 May 9. Mol Psychiatry. 2018. PMID: 28485405
Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state.
Tietze E, Barbosa AR, Araujo B, Euclydes V, Spiegelberg B, Cho HJ, Lee YK, Wang Y, McCord A, Lorenzetti A, Feltrin A, van de Leemput J, Di Carlo P, Ursini G, Benjamin KJ, Brentani H, Kleinman JE, Hyde TM, Weinberger DR, McKay R, Shin JH, Sawada T, Paquola ACM, Erwin JA. Tietze E, et al. Among authors: kleinman je. Sci Rep. 2024 Feb 8;14(1):3291. doi: 10.1038/s41598-024-53381-w. Sci Rep. 2024. PMID: 38332235 Free PMC article.
BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders.
BrainSeq: A Human Brain Genomics Consortium. Electronic address: drweinberger@libd.org; BrainSeq: A Human Brain Genomics Consortium. BrainSeq: A Human Brain Genomics Consortium. Electronic address: drweinberger@libd.org, et al. Neuron. 2015 Dec 16;88(6):1078-1083. doi: 10.1016/j.neuron.2015.10.047. Neuron. 2015. PMID: 26687217 Free article. Review.
385 results