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Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus.
Dillard JA, Taft-Benz SA, Knight AC, Anderson EJ, Pressey KD, Parotti B, Martinez SA, Diaz JL, Sarkar S, Madden EA, De la Cruz G, Adams LE, Dinnon KH 3rd, Leist SR, Martinez DR, Schäfer A, Powers JM, Yount BL Jr, Castillo IN, Morales NL, Burdick J, Evangelista MKD, Ralph LM, Pankow NC, Linnertz CL, Lakshmanane P, Montgomery SA, Ferris MT, Baric RS, Baxter VK, Heise MT. Dillard JA, et al. Among authors: linnertz cl. Nat Commun. 2024 May 3;15(1):3738. doi: 10.1038/s41467-024-47450-x. Nat Commun. 2024. PMID: 38702297 Free PMC article.
A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice.
Risemberg EL, Smeekens JM, Cruz Cisneros MC, Hampton BK, Hock P, Linnertz CL, Miller DR, Orgel K, Shaw GD, Manuel de Villena FP, Burks AW, Valdar W, Kulis MD, Ferris MT. Risemberg EL, et al. Among authors: linnertz cl. J Allergy Clin Immunol. 2024 Apr 24:S0091-6749(24)00411-1. doi: 10.1016/j.jaci.2024.03.027. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 38670234
Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans.
Schäfer A, Gralinski LE, Leist SR, Hampton BK, Mooney MA, Jensen KL, Graham RL, Agnihothram S, Jeng S, Chamberlin S, Bell TA, Scobey DT, Linnertz CL, VanBlargan LA, Thackray LB, Hock P, Miller DR, Shaw GD, Diamond MS, de Villena FPM, McWeeney SK, Heise MT, Menachery VD, Ferris MT, Baric RS. Schäfer A, et al. Among authors: linnertz cl. Virus Res. 2024 Jun;344:199357. doi: 10.1016/j.virusres.2024.199357. Epub 2024 Mar 23. Virus Res. 2024. PMID: 38508400 Free PMC article.
A mutation in Themis contributes to peanut-induced oral anaphylaxis in CC027 mice.
Risemberg EL, Smeekens JM, Cisneros MCC, Hampton BK, Hock P, Linnertz CL, Miller DR, Orgel K, Shaw GD, de Villena FPM, Burks AW, Valdar W, Kulis MD, Ferris MT. Risemberg EL, et al. Among authors: linnertz cl. bioRxiv [Preprint]. 2023 Sep 13:2023.09.13.557467. doi: 10.1101/2023.09.13.557467. bioRxiv. 2023. PMID: 37745496 Free PMC article. Updated. Preprint.
Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice.
Brown AJ, Won JJ, Wolfisberg R, Fahnøe U, Catanzaro N, West A, Moreira FR, Nogueira Batista M, Ferris MT, Linnertz CL, Leist SR, Nguyen C, De la Cruz G, Midkiff BR, Xia Y, Evangelista MD, Montgomery SA, Billerbeck E, Bukh J, Scheel TKH, Rice CM, Sheahan TP. Brown AJ, et al. Among authors: linnertz cl. Hepatology. 2024 Jan 1;79(1):183-197. doi: 10.1097/HEP.0000000000000547. Epub 2023 Aug 7. Hepatology. 2024. PMID: 37540195 Free PMC article.
Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis.
Hampton BK, Plante KS, Whitmore AC, Linnertz CL, Madden EA, Noll KE, Boyson SP, Parotti B, Xenakis JG, Bell TA, Hock P, Shaw GD, de Villena FP, Ferris MT, Heise MT. Hampton BK, et al. Among authors: linnertz cl. PLoS Genet. 2022 Dec 27;18(12):e1010548. doi: 10.1371/journal.pgen.1010548. eCollection 2022 Dec. PLoS Genet. 2022. PMID: 36574452 Free PMC article.
Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward.
Beierle JA, Yao EJ, Goldstein SI, Lynch WB, Scotellaro JL, Shah AA, Sena KD, Wong AL, Linnertz CL, Averin O, Moody DE, Reilly CA, Peltz G, Emili A, Ferris MT, Bryant CD. Beierle JA, et al. Among authors: linnertz cl. J Pharmacol Exp Ther. 2022 Aug;382(2):167-180. doi: 10.1124/jpet.122.001217. Epub 2022 Jun 10. J Pharmacol Exp Ther. 2022. PMID: 35688478 Free PMC article.
Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice.
Smith CM, Baker RE, Proulx MK, Mishra BB, Long JE, Park SW, Lee HN, Kiritsy MC, Bellerose MM, Olive AJ, Murphy KC, Papavinasasundaram K, Boehm FJ, Reames CJ, Meade RK, Hampton BK, Linnertz CL, Shaw GD, Hock P, Bell TA, Ehrt S, Schnappinger D, Pardo-Manuel de Villena F, Ferris MT, Ioerger TR, Sassetti CM. Smith CM, et al. Among authors: linnertz cl. Elife. 2022 Feb 3;11:e74419. doi: 10.7554/eLife.74419. Elife. 2022. PMID: 35112666 Free PMC article.