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Genetic susceptibility, evolution and the kuru epidemic.
Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Beck J, Campbell T, Al-Dujaily H, Hummerich H, Alpers MP, Collinge J. Mead S, et al. Among authors: campbell t. Philos Trans R Soc Lond B Biol Sci. 2008 Nov 27;363(1510):3741-6. doi: 10.1098/rstb.2008.0087. Philos Trans R Soc Lond B Biol Sci. 2008. PMID: 18849290 Free PMC article.
A novel protective prion protein variant that colocalizes with kuru exposure.
Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Campbell T, Al-Dujaily H, Hummerich H, Beck J, Mein CA, Verzilli C, Whittaker J, Alpers MP, Collinge J. Mead S, et al. Among authors: campbell t. N Engl J Med. 2009 Nov 19;361(21):2056-65. doi: 10.1056/NEJMoa0809716. N Engl J Med. 2009. PMID: 19923577 Free article.
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Mead S, Uphill J, Beck J, Poulter M, Campbell T, Lowe J, Adamson G, Hummerich H, Klopp N, Rückert IM, Wichmann HE, Azazi D, Plagnol V, Pako WH, Whitfield J, Alpers MP, Whittaker J, Balding DJ, Zerr I, Kretzschmar H, Collinge J. Mead S, et al. Among authors: campbell t. Hum Mol Genet. 2012 Apr 15;21(8):1897-906. doi: 10.1093/hmg/ddr607. Epub 2011 Dec 30. Hum Mol Genet. 2012. PMID: 22210626 Free PMC article.
Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.
Mead S, Poulter M, Uphill J, Beck J, Whitfield J, Webb TE, Campbell T, Adamson G, Deriziotis P, Tabrizi SJ, Hummerich H, Verzilli C, Alpers MP, Whittaker JC, Collinge J. Mead S, et al. Among authors: campbell t. Lancet Neurol. 2009 Jan;8(1):57-66. doi: 10.1016/S1474-4422(08)70265-5. Lancet Neurol. 2009. PMID: 19081515 Free PMC article.
Rare structural genetic variation in human prion diseases.
Lukic A, Uphill J, Brown CA, Beck J, Poulter M, Campbell T, Adamson G, Hummerich H, Whitfield J, Ponto C, Zerr I, Lloyd SE, Collinge J, Mead S. Lukic A, et al. Among authors: campbell t. Neurobiol Aging. 2015 May;36(5):2004.e1-8. doi: 10.1016/j.neurobiolaging.2015.01.011. Epub 2015 Jan 22. Neurobiol Aging. 2015. PMID: 25726360
Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population.
Beck J, Poulter M, Hensman D, Rohrer JD, Mahoney CJ, Adamson G, Campbell T, Uphill J, Borg A, Fratta P, Orrell RW, Malaspina A, Rowe J, Brown J, Hodges J, Sidle K, Polke JM, Houlden H, Schott JM, Fox NC, Rossor MN, Tabrizi SJ, Isaacs AM, Hardy J, Warren JD, Collinge J, Mead S. Beck J, et al. Among authors: campbell t. Am J Hum Genet. 2013 Mar 7;92(3):345-53. doi: 10.1016/j.ajhg.2013.01.011. Epub 2013 Feb 21. Am J Hum Genet. 2013. PMID: 23434116 Free PMC article.
1,896 results