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Targeting Neuroinflammation by Pharmacologic Downregulation of Inflammatory Pathways Is Neuroprotective in Protein Misfolding Disorders.
ACS Chem Neurosci. 2024 Apr 3;15(7):1533-1547. doi: 10.1021/acschemneuro.3c00846. Epub 2024 Mar 20.
ACS Chem Neurosci. 2024.
PMID: 38507813
Intranasally delivered mesenchymal stromal cells decrease glial inflammation early in prion disease.
Hay AJD, Latham AS, Mumford G, Hines AD, Risen S, Gordon E, Siebenaler C, Gilberto VS, Zabel MD, Moreno JA.
Hay AJD, et al. Among authors: latham as.
Front Neurosci. 2023 May 12;17:1158408. doi: 10.3389/fnins.2023.1158408. eCollection 2023.
Front Neurosci. 2023.
PMID: 37250395
Free PMC article.
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Activated gliosis, accumulation of amyloid β, and hyperphosphorylation of tau in aging canines with and without cognitive decline.
Hines AD, McGrath S, Latham AS, Kusick B, Mulligan L, Richards ML, Moreno JA.
Hines AD, et al. Among authors: latham as.
Front Aging Neurosci. 2023 Apr 27;15:1128521. doi: 10.3389/fnagi.2023.1128521. eCollection 2023.
Front Aging Neurosci. 2023.
PMID: 37304080
Free PMC article.
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Biological agents and the aging brain: glial inflammation and neurotoxic signaling.
Latham AS, Moreno JA, Geer CE.
Latham AS, et al.
Front Aging. 2023 Aug 15;4:1244149. doi: 10.3389/fragi.2023.1244149. eCollection 2023.
Front Aging. 2023.
PMID: 37649972
Free PMC article.
Review.
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Gliosis, misfolded protein aggregation, and neuronal loss in a guinea pig model of pulmonary tuberculosis.
Latham AS, Geer CE, Ackart DF, Anderson IK, Vittoria KM, Podell BK, Basaraba RJ, Moreno JA.
Latham AS, et al.
Front Neurosci. 2023 May 19;17:1157652. doi: 10.3389/fnins.2023.1157652. eCollection 2023.
Front Neurosci. 2023.
PMID: 37274195
Free PMC article.
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A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.
Rocha SM, Fagre AC, Latham AS, Cummings JE, Aboellail TA, Reigan P, Aldaz DA, McDermott CP, Popichak KA, Kading RC, Schountz T, Theise ND, Slayden RA, Tjalkens RB.
Rocha SM, et al. Among authors: latham as.
Front Immunol. 2022 Feb 16;13:811430. doi: 10.3389/fimmu.2022.811430. eCollection 2022.
Front Immunol. 2022.
PMID: 35250984
Free PMC article.
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Neuroprotective Efficacy of the Glucocorticoid Receptor Modulator PT150 in the Rotenone Mouse Model of Parkinson's Disease.
Latham AS, Rocha SM, McDermott CP, Reigan P, Slayden RA, Tjalkens RB.
Latham AS, et al.
bioRxiv [Preprint]. 2024 Apr 15:2024.04.12.589261. doi: 10.1101/2024.04.12.589261.
bioRxiv. 2024.
PMID: 38659796
Free PMC article.
Preprint.
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