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Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.
Appelbaum J, Price AE, Oda K, Zhang J, Leung WH, Tampella G, Xia D, So PP, Hilton SK, Evandy C, Sarkar S, Martin U, Krostag AR, Leonardi M, Zak DE, Logan R, Lewis P, Franke-Welch S, Ngwenyama N, Fitzgerald M, Tulberg N, Rawlings-Rhea S, Gardner RA, Jones K, Sanabria A, Crago W, Timmer J, Hollands A, Eckelman B, Bilic S, Woodworth J, Lamble A, Gregory PD, Jarjour J, Pogson M, Gustafson JA, Astrakhan A, Jensen MC. Appelbaum J, et al. Among authors: ngwenyama n. J Clin Invest. 2024 Mar 19;134(9):e162593. doi: 10.1172/JCI162593. J Clin Invest. 2024. PMID: 38502193 Free PMC article. Clinical Trial.
Antigen presentation by cardiac fibroblasts promotes cardiac dysfunction.
Ngwenyama N, Kaur K, Bugg D, Theall B, Aronovitz M, Berland R, Panagiotidou S, Genco C, Perrin MA, Davis J, Alcaide P. Ngwenyama N, et al. Nat Cardiovasc Res. 2022 Aug;1(8):761-774. doi: 10.1038/s44161-022-00116-7. Epub 2022 Aug 12. Nat Cardiovasc Res. 2022. PMID: 36092510 Free PMC article.
Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis.
Man JJ, Lu Q, Moss ME, Carvajal B, Baur W, Garza AE, Freeman R, Anastasiou M, Ngwenyama N, Adler GK, Alcaide P, Jaffe IZ. Man JJ, et al. Among authors: ngwenyama n. Arterioscler Thromb Vasc Biol. 2021 Nov;41(11):2740-2755. doi: 10.1161/ATVBAHA.121.316929. Epub 2021 Oct 7. Arterioscler Thromb Vasc Biol. 2021. PMID: 34615372 Free PMC article.
Heart Inflammation: Immune Cell Roles and Roads to the Heart.
Carrillo-Salinas FJ, Ngwenyama N, Anastasiou M, Kaur K, Alcaide P. Carrillo-Salinas FJ, et al. Among authors: ngwenyama n. Am J Pathol. 2019 Aug;189(8):1482-1494. doi: 10.1016/j.ajpath.2019.04.009. Epub 2019 May 18. Am J Pathol. 2019. PMID: 31108102 Free PMC article. Review.
19 results