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Self-assembling protein nanocarrier for selective delivery of cytotoxic polypeptides to CXCR4+ head and neck squamous cell carcinoma tumors.
Rioja-Blanco E, Arroyo-Solera I, Álamo P, Casanova I, Gallardo A, Unzueta U, Serna N, Sánchez-García L, Quer M, Villaverde A, Vázquez E, Mangues R, Alba-Castellón L, León X. Rioja-Blanco E, et al. Among authors: alamo p. Acta Pharm Sin B. 2022 May;12(5):2578-2591. doi: 10.1016/j.apsb.2021.09.030. Epub 2021 Oct 14. Acta Pharm Sin B. 2022. PMID: 35646535 Free PMC article.
A Novel CXCR4-Targeted Diphtheria Toxin Nanoparticle Inhibits Invasion and Metastatic Dissemination in a Head and Neck Squamous Cell Carcinoma Mouse Model.
Rioja-Blanco E, Gallardo A, Arroyo-Solera I, Álamo P, Casanova I, Unzueta U, Serna N, Sánchez-García L, Quer M, Villaverde A, Vázquez E, León X, Alba-Castellón L, Mangues R. Rioja-Blanco E, et al. Among authors: alamo p. Pharmaceutics. 2022 Apr 18;14(4):887. doi: 10.3390/pharmaceutics14040887. Pharmaceutics. 2022. PMID: 35456719 Free PMC article.
A diphtheria toxin-based nanoparticle achieves specific cytotoxic effect on CXCR4+ lymphoma cells without toxicity in immunocompromised and immunocompetent mice.
Falgàs A, Garcia-León A, Núñez Y, Serna N, Sánchez-Garcia L, Unzueta U, Voltà-Durán E, Aragó M, Álamo P, Alba-Castellón L, Sierra J, Gallardo A, Villaverde A, Vázquez E, Mangues R, Casanova I. Falgàs A, et al. Among authors: alamo p. Biomed Pharmacother. 2022 Jun;150:112940. doi: 10.1016/j.biopha.2022.112940. Epub 2022 Apr 11. Biomed Pharmacother. 2022. PMID: 35421785 Free article.
CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma.
Rioja-Blanco E, Arroyo-Solera I, Álamo P, Casanova I, Gallardo A, Unzueta U, Serna N, Sánchez-García L, Quer M, Villaverde A, Vázquez E, León X, Alba-Castellón L, Mangues R. Rioja-Blanco E, et al. Among authors: alamo p. J Exp Clin Cancer Res. 2022 Feb 4;41(1):49. doi: 10.1186/s13046-022-02267-8. J Exp Clin Cancer Res. 2022. PMID: 35120582 Free PMC article.
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.
Pallarès V, Unzueta U, Falgàs A, Aviñó A, Núñez Y, García-León A, Sánchez-García L, Serna N, Gallardo A, Alba-Castellón L, Álamo P, Sierra J, Cedó L, Eritja R, Villaverde A, Vázquez E, Casanova I, Mangues R. Pallarès V, et al. Among authors: alamo p. Biomaterials. 2022 Jan;280:121258. doi: 10.1016/j.biomaterials.2021.121258. Epub 2021 Nov 24. Biomaterials. 2022. PMID: 34847435 Free article.
36 results