Quémard A - Search Results

1

HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II: A singular structure for a unique function.

Bories P, Rima J, Tranier S, Marcoux J, Grimoire Y, Tomaszczyk M, Launay A, Fata K, Marrakchi H, Burlet-Schiltz O, Mourey L, Ducoux-Petit M, Bardou F, Bon C, Quémard A. Bories P, et al. Among authors: quemard a. Protein Sci. 2024 Apr;33(4):e4964. doi: 10.1002/pro.4964. Protein Sci. 2024. PMID: 38501584 Free PMC article.

2

Acylation of glycerolipids in mycobacteria.

Angala SK, Carreras-Gonzalez A, Huc-Claustre E, Anso I, Kaur D, Jones V, Palčeková Z, Belardinelli JM, de Sousa-d'Auria C, Shi L, Slama N, Houssin C, Quémard A, McNeil M, Guerin ME, Jackson M. Angala SK, et al. Among authors: quemard a. Nat Commun. 2023 Oct 23;14(1):6694. doi: 10.1038/s41467-023-42478-x. Nat Commun. 2023. PMID: 37872138 Free PMC article.

3

Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis.

Bon C, Cabantous S, Julien S, Guillet V, Chalut C, Rima J, Brison Y, Malaga W, Sanchez-Dafun A, Gavalda S, Quémard A, Marcoux J, Waldo GS, Guilhot C, Mourey L. Bon C, et al. Among authors: quemard a. BMC Biol. 2022 Jun 21;20(1):147. doi: 10.1186/s12915-022-01337-9. BMC Biol. 2022. PMID: 35729566 Free PMC article.

4

Correction: Pleiotropic Effect of AccD5 and AccE5 Depletion in Acyl-Coenzyme A Carboxylase Activity and in Lipid Biosynthesis in Mycobacteria.

Lyonnet BB, Diacovich L, Cabruja M, Bardou F, Quémard A, Gago G, Gramajo H. Lyonnet BB, et al. Among authors: quemard a. PLoS One. 2020 Nov 11;15(11):e0242528. doi: 10.1371/journal.pone.0242528. eCollection 2020. PLoS One. 2020. PMID: 33175908 Free PMC article.

5

Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis.

Lefebvre C, Frigui W, Slama N, Lauzeral-Vizcaino F, Constant P, Lemassu A, Parish T, Eynard N, Daffé M, Brosch R, Quémard A. Lefebvre C, et al. Among authors: quemard a. Sci Rep. 2020 Feb 7;10(1):2112. doi: 10.1038/s41598-020-58967-8. Sci Rep. 2020. PMID: 32034201 Free PMC article.

6

HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness.

Lefebvre C, Boulon R, Ducoux M, Gavalda S, Laval F, Jamet S, Eynard N, Lemassu A, Cam K, Bousquet MP, Bardou F, Burlet-Schiltz O, Daffé M, Quémard A. Lefebvre C, et al. Among authors: quemard a. Sci Rep. 2018 Apr 16;8(1):6034. doi: 10.1038/s41598-018-24380-5. Sci Rep. 2018. PMID: 29662082 Free PMC article.

7

Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.

Faille A, Gavalda S, Slama N, Lherbet C, Maveyraud L, Guillet V, Laval F, Quémard A, Mourey L, Pedelacq JD. Faille A, et al. Among authors: quemard a. J Mol Biol. 2017 May 19;429(10):1554-1569. doi: 10.1016/j.jmb.2017.03.026. Epub 2017 Apr 1. J Mol Biol. 2017. PMID: 28377293

8

Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits.

Bazet Lyonnet B, Diacovich L, Gago G, Spina L, Bardou F, Lemassu A, Quémard A, Gramajo H. Bazet Lyonnet B, et al. Among authors: quemard a. FEBS J. 2017 Apr;284(7):1110-1125. doi: 10.1111/febs.14046. Epub 2017 Mar 19. FEBS J. 2017. PMID: 28222482 Free PMC article.

9

Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis.

Chollet A, Stigliani JL, Pasca MR, Mori G, Lherbet C, Constant P, Quémard A, Bernadou J, Pratviel G, Bernardes-Génisson V. Chollet A, et al. Among authors: quemard a. Chem Biol Drug Des. 2016 Nov;88(5):740-755. doi: 10.1111/cbdd.12804. Epub 2016 Jul 16. Chem Biol Drug Des. 2016. PMID: 27301022

10

New Insights into the Mycolate-Containing Compound Biosynthesis and Transport in Mycobacteria.

Quémard A. Quémard A. Trends Microbiol. 2016 Sep;24(9):725-738. doi: 10.1016/j.tim.2016.04.009. Epub 2016 Jun 3. Trends Microbiol. 2016. PMID: 27268593 Review.

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