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Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, Benyamini H, Copty J, Ravishankar S, Morrow A, Mitchel J, Neavin D, Gupta R, Farbehi N, Grundman J, Myers RH, Scherzer CR, Trojanowski JQ, Van Deerlin VM, Cooper AA, Lee EB, Erlich Y, Lindquist S, Peng J, Geschwind DH, Powell J, Studer L, Feany MB, Sunyaev SR, Khurana V. Nazeen S, et al. Among authors: erlich y. bioRxiv [Preprint]. 2024 Mar 7:2024.03.03.583145. doi: 10.1101/2024.03.03.583145. bioRxiv. 2024. PMID: 38496508 Free PMC article. Preprint.
Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamti A, Falciatori I, Berkyurek AC, Rasnic R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: erlich y. bioRxiv [Preprint]. 2022 Apr 12:2022.04.12.488010. doi: 10.1101/2022.04.12.488010. bioRxiv. 2022. PMID: 35441162 Free PMC article. Updated. Preprint.
From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamati A, Falciatori I, Berkyurek AC, Rasnic R, Izuagbe R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: erlich y. Commun Biol. 2023 Mar 16;6(1):277. doi: 10.1038/s42003-023-04589-5. Commun Biol. 2023. PMID: 36928598 Free PMC article.
Complicated legacies: The human genome at 20.
Jones KM, Cook-Deegan R, Rotimi CN, Callier SL, Bentley AR, Stevens H, Phillips KA, Jansen JP, Weyant CF, Roberts DE, Zielinski D, Erlich Y, Garrison NA, Carroll SR, Ossorio PN, Moreau Y, Wang M. Jones KM, et al. Among authors: erlich y. Science. 2021 Feb 5;371(6529):564-569. doi: 10.1126/science.abg5266. Epub 2021 Feb 4. Science. 2021. PMID: 33542123 Free PMC article.
Database shares that transform research subjects into partners.
Kain R, Kahn S, Thompson D, Lewis D, Barker D, Bustamante C, Cabou C, Casdin A, Garcia F, Paragas J, Patrinos A, Rajagopal A, Terry SF, Van Zeeland A, Yu E, Erlich Y, Barry D. Kain R, et al. Among authors: erlich y. Nat Biotechnol. 2019 Oct;37(10):1112-1115. doi: 10.1038/s41587-019-0278-9. Nat Biotechnol. 2019. PMID: 31537916 No abstract available.
Estimating variance components in population scale family trees.
Shor T, Kalka I, Geiger D, Erlich Y, Weissbrod O. Shor T, et al. Among authors: erlich y. PLoS Genet. 2019 May 9;15(5):e1008124. doi: 10.1371/journal.pgen.1008124. eCollection 2019 May. PLoS Genet. 2019. PMID: 31071088 Free PMC article.
65 results