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Neutrophil elastase as a versatile cleavage enzyme for activation of αvβ3 integrin-targeted small molecule drug conjugates with different payload classes in the tumor microenvironment.
Rebstock AS, Wiedmann M, Stelte-Ludwig B, Wong H, Johnson AJ, Izumi R, Hamdy A, Lerchen HG. Rebstock AS, et al. Among authors: wong h. Front Pharmacol. 2024 Mar 1;15:1358393. doi: 10.3389/fphar.2024.1358393. eCollection 2024. Front Pharmacol. 2024. PMID: 38495100 Free PMC article.
Discovery of VIP236, an αvβ3-Targeted Small-Molecule-Drug Conjugate with Neutrophil Elastase-Mediated Activation of 7-Ethyl Camptothecin Payload for Treatment of Solid Tumors.
Lerchen HG, Stelte-Ludwig B, Heroult M, Zubov D, Gericke KM, Wong H, Frigault MM, Johnson AJ, Izumi R, Hamdy A. Lerchen HG, et al. Among authors: wong h. Cancers (Basel). 2023 Sep 1;15(17):4381. doi: 10.3390/cancers15174381. Cancers (Basel). 2023. PMID: 37686656 Free PMC article.
Bowel and mesenteric injuries in blunt abdominal injury.
Wong HL, Shi H, Teoh WC, Liu JJ. Wong HL, et al. Singapore Med J. 2024 Jun 1;65(6):354-359. doi: 10.4103/singaporemedj.SMJ-2022-023. Epub 2024 Jun 4. Singapore Med J. 2024. PMID: 38834940 Free article. No abstract available.
Extrafibrillar demineralization: Yes or no?
Zhou Q, Li Y, Xiao T, Zhong Q, Wu L, Zhou Z, Wong H, Li QL. Zhou Q, et al. Among authors: wong h. Dent Mater. 2024 May 30:S0109-5641(24)00115-5. doi: 10.1016/j.dental.2024.05.017. Online ahead of print. Dent Mater. 2024. PMID: 38821839
4,940 results