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Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance.
Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG. Palma FR, et al. Among authors: danes jm. Cell Rep. 2024 Mar 26;43(3):113897. doi: 10.1016/j.celrep.2024.113897. Epub 2024 Mar 16. Cell Rep. 2024. PMID: 38493478 Free article.
Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
Coelho DR, Palma FR, Paviani V, He C, Danes JM, Huang Y, Calado JCP, Hart PC, Furdui CM, Poole LB, Schipma MJ, Bonini MG. Coelho DR, et al. Among authors: danes jm. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2110348119. doi: 10.1073/pnas.2110348119. Epub 2022 Jul 14. Proc Natl Acad Sci U S A. 2022. PMID: 35858297 Free PMC article.
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG. He C, et al. Among authors: danes jm. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. doi: 10.1073/pnas.1902308116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591207 Free PMC article.
AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism.
Palma FR, Ratti BA, Paviani V, Coelho DR, Miguel R, Danes JM, Zaichik SV, de Abreu AL, Silva SO, Chen Y, Silverstein RL, Karan U, Jones DP, Bonini MG. Palma FR, et al. Among authors: danes jm. Oncogene. 2021 Sep;40(36):5455-5467. doi: 10.1038/s41388-021-01943-x. Epub 2021 Jul 21. Oncogene. 2021. PMID: 34290400 Free PMC article.
15 results