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The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host.
Bexkens ML, Martin OMF, van den Heuvel JM, Schmitz MGJ, Teusink B, Bakker BM, van Hellemond JJ, Haanstra JR, Walkinshaw MD, Tielens AGM. Bexkens ML, et al. Among authors: walkinshaw md. Int J Parasitol. 2024 Mar 15:S0020-7519(24)00054-7. doi: 10.1016/j.ijpara.2024.03.005. Online ahead of print. Int J Parasitol. 2024. PMID: 38492780 Free article.
Peripheral blood immune cell profiling of acute corneal transplant rejection.
Hjortdal J, Griffin MD, Cadoux M, Armitage WJ, Bylesjo M, Gabhann PM, Murphy CC, Pleyer U, Tole D, Vabres B, Walkinshaw MD, Gourraud PA, Karakachoff M, Brouard S, Degauque N. Hjortdal J, et al. Among authors: walkinshaw md. Am J Transplant. 2022 Oct;22(10):2337-2347. doi: 10.1111/ajt.17119. Epub 2022 Jun 29. Am J Transplant. 2022. PMID: 35704290 Free PMC article.
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
McNae IW, Kinkead J, Malik D, Yen LH, Walker MK, Swain C, Webster SP, Gray N, Fernandes PM, Myburgh E, Blackburn EA, Ritchie R, Austin C, Wear MA, Highton AJ, Keats AJ, Vong A, Dornan J, Mottram JC, Michels PAM, Pettit S, Walkinshaw MD. McNae IW, et al. Among authors: walkinshaw md. Nat Commun. 2021 Feb 16;12(1):1052. doi: 10.1038/s41467-021-21273-6. Nat Commun. 2021. PMID: 33594070 Free PMC article.
Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase.
Pinto Torres JE, Yuan M, Goossens J, Versées W, Caljon G, Michels PA, Walkinshaw MD, Magez S, Sterckx YG. Pinto Torres JE, et al. Among authors: walkinshaw md. Mol Biochem Parasitol. 2020 Mar;236:111263. doi: 10.1016/j.molbiopara.2020.111263. Epub 2020 Feb 19. Mol Biochem Parasitol. 2020. PMID: 32084384
193 results