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SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function.
Bouti P, Klein BJAM, Verkuijlen PJH, Schornagel K, van Alphen FPJ, Taris KH, van den Biggelaar M, Hoogendijk AJ, van Bruggen R, Kuijpers TW, Matlung HL. Bouti P, et al. Among authors: van alphen fpj. Front Immunol. 2024 Feb 29;15:1344761. doi: 10.3389/fimmu.2024.1344761. eCollection 2024. Front Immunol. 2024. PMID: 38487529 Free PMC article.
Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components.
Gazendam RP, van de Geer A, van Hamme JL, Tool AT, van Rees DJ, Aarts CE, van den Biggelaar M, van Alphen F, Verkuijlen P, Meijer AB, Janssen H, Roos D, van den Berg TK, Kuijpers TW. Gazendam RP, et al. Haematologica. 2016 May;101(5):587-96. doi: 10.3324/haematol.2015.136630. Epub 2016 Jan 22. Haematologica. 2016. PMID: 26802050 Free PMC article.
Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency.
Kuijpers TW, Tool ATJ, van der Bijl I, de Boer M, van Houdt M, de Cuyper IM, Roos D, van Alphen F, van Leeuwen K, Cambridge EL, Arends MJ, Dougan G, Clare S, Ramirez-Solis R, Pals ST, Adams DJ, Meijer AB, van den Berg TK. Kuijpers TW, et al. J Allergy Clin Immunol. 2017 Jul;140(1):273-277.e10. doi: 10.1016/j.jaci.2016.09.061. Epub 2016 Dec 10. J Allergy Clin Immunol. 2017. PMID: 27965109 No abstract available.
Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.
van den Eshof BL, Hoogendijk AJ, Simpson PJ, van Alphen FPJ, Zanivan S, Mertens K, Meijer AB, van den Biggelaar M. van den Eshof BL, et al. Among authors: van den biggelaar m, van alphen fpj. Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1891-1902. doi: 10.1161/ATVBAHA.117.309926. Epub 2017 Aug 17. Arterioscler Thromb Vasc Biol. 2017. PMID: 28818855 Free article.
Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages.
Heideveld E, Hampton-O'Neil LA, Cross SJ, van Alphen FPJ, van den Biggelaar M, Toye AM, van den Akker E. Heideveld E, et al. Among authors: van den biggelaar m, van den akker e, van alphen fpj. Haematologica. 2018 Mar;103(3):395-405. doi: 10.3324/haematol.2017.179341. Epub 2017 Dec 28. Haematologica. 2018. PMID: 29284682 Free PMC article.
Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.
Salerno F, Engels S, van den Biggelaar M, van Alphen FPJ, Guislain A, Zhao W, Hodge DL, Bell SE, Medema JP, von Lindern M, Turner M, Young HA, Wolkers MC. Salerno F, et al. Among authors: van den biggelaar m, van alphen fpj. Nat Immunol. 2018 Aug;19(8):828-837. doi: 10.1038/s41590-018-0155-6. Epub 2018 Jul 9. Nat Immunol. 2018. PMID: 29988089 Free PMC article.
A Homozygous Mutation on the HBA1 Gene Coding for Hb Charlieu (HBA1: c.320T>C) Together with β-Thalassemia Trait Results in Severe Hemolytic Anemia.
Klei TRL, Kheradmand Kia S, Veldthuis M, Dehbozorgian J, Karimi M, Geissler J, Sellink E, Thiel-Valkhof M, Burger P, van Alphen F, Meijer AB, van Bruggen R, van Zwieten R. Klei TRL, et al. Hemoglobin. 2019 Mar;43(2):77-82. doi: 10.1080/03630269.2019.1601107. Epub 2019 Jun 13. Hemoglobin. 2019. PMID: 31190578
56 results